A new neurologist wants me to take re quip with the sinemet and then reduce the sinemet. I am taking 25/100 4x of sinemet at present. Has anyone done this with success? The sinemet gives me swallowing problems and dyskinesia. Also anyone take LDN with requip? I am also having major problems with off times when I can't walk and at night when I have to get up for the bathroom. Please help!