I tried to take selegeline with sinemet 25/100 4xday. I quit after a week because the dyskinesia was so bad. My neuro did not discuss with me how or when to reduce the sinemet. I would like to try it again. I felt better motor skills. The sinemet lasted much longer. Does anyone have experience with this? I need something to keep me going for a longer period of time. No patch/bad experience.