Do you use medical Marijuana?

Hi, I am interested in communicating with PWP who use medical Marijuana as an adjunct to there Dr. prescribed meds. How and when and what relief specifically do you get, What benefits do you derive and how often you take, Anything applicable to you and your use of Marijuana as a Parkinson med. I would appreciate hearing from folks with no bias and who are genuinely interested in this topic.Thank you, Scotty T

60 Replies

  • Since I live in a state that still outlaws Reefer, I cannot answer this scientifically. But I would say that the change of mind that POT engenders sometimes helps get me through the night. It can cause increased anxiety in some people, including me. Paranoia. left over from the old days( flashback to the future). it doesn't help my guitar playing, nothing does, but helps my wife tune me out. Flying V cute check out this my first singing gig

  • this was great -- what a nice event. I too inflict my singing on anyone who can't run away. PD or no because I can. No opinion about the medical marijuana, but keeping an open mind since I feel like a lab animal trying out different meds. Just came off namenda and rescheduling my sinemet through the day to avoid dyskinesia. I feel happy again, now and then :D

  • If you are in Florida it looks like medical Marijuana will soon be on the books, Hope so!

  • I am waiting for my state to join in...

  • It's not available in the UK

  • Froggatt you may find this interesting re situation in UK

  • Thanks Hikoi

  • I live in the UK and have tried cannabis for my PD but it makes me too anxious. But if it did help me I would not worry about the legality personally, if I got arrested for possession of cannabis I would use it as an opportunity to draw attention to the ridiculous situation that exists - where a plant that helps so many health conditions is illegal. I have never heard of someone with a health condition in the UK being convicted for using cannabis.

  • Hi, May I suggest you use MM before you go to sleep to alleviate any anxiety, Thats what I do and I sleep like a baby. Good Luck.

  • I am very interested in MM in terms of providing relief of my symptoms - your link a most interesting! My only worry about taking it illegally is that you are outside the system and your overall assessments would therefore not take M into account. I would also be concerned about the purity of the product and it's ongoing availability. These concerns probably reflect my "innocence" in these matters LOL

  • I would tell my neurologist that I was benefitting from MM if it helped me. I see it as much my job to educate them as it is theirs to educate me. There are places you can order MM from which are trustworthy and will tell you exactly what the chemical make up is but I guess in the US states where it is illegal it might be too risky. In the UK police generally regard possession of cannabis as not worth the paperwork!

  • Aye - there's the rub "if it helped me" it would be a no-brainer if we knew it would help us Where do we start? What dosage and how often?

    Interestingly, the granddaughter of a friend of mine offered to get me some M but I refrained!!

    I think the way to proceed in the UK is to follow the arrangement by which MS people can get it, I am going to write to my MP copying that Link you sent and asking him to lend his support to a bit of Research as to whether MM would benefit us (I will see what research has been done in the UK - presumably the MS charity must have done some?)

    I will also write the same to Parkinson's UK, Cure Parkinson's Trust and the European organisation (can't remember their acronym but will find them) with a copy to my MEP

    Call me Don Quixote LOL

  • I was misdiagnosed with MS and know that the MS Society doesn't condone cannabis use (or anything else 'alternative'. These organisations are very conservative! It is being used a lot for curing cancer, what we really need is it to be legalised, at least for medical use, like in certain states of the US.

  • I would start with smoking a joint of something milder than skunk and seeing if it helps...

  • Don't worry about assessments not taking MM into account. All they do is measure the rate at which we are declining and prescribe drugs that have terrible side effects and don't affect the disease process. MM may slow the progression of the disease, and allow you to take less sinemet. Your assessments will just show that you are doing better than you would be otherwise. For peace of mind you can carry a wallet card that lists your meds in the prescribed amounts in case of emergency.

  • Very interested. See my post this morning. Also, Google Phoenix Tears and Rick Simpson.

  • Thank You for your response, I use the hash oil Rick Simpson recommends.

  • I have just received my OR card. I was approved for pain, anxiety, dystonia and insomnia. Indica is the preferred strain. I have a pencil vaporizer, but have not mastered it yet. It is difficult to determine the best dosage that doesn't get me too stoned. I do think it is beneficial when the dystonia is elevated. It also helps sleeping.

    Being a former percussionist, I frequently play "air drums". I was amazed one morning when I was particularly slow. I inhaled a very small amount from the vaporizer and sat down to listen to Maha Vishnu Orchestra... Birds of fire. I quickly got in tempo with Billy Cobham in one of his most driven perfomances.

    Go to: for a summary of medicinal properties.

  • Thanks and I appreciate the response, We can learn from each others experience.

  • Lest I forget.... Shortly after I retired 5 years ago, my neighbor shared some cannabis wth me while I was taking Azilect. On 2 occasions I lost blood pressure to the point of lying on the floor for 45 minutes before I could sit up and eventually stand. I would caution any use with mao inhibitors.

  • I used to be a professional musician now I just pick at home and read this blog….

  • Great group! I like the album "Inner Mounting Flame"

  • Scotty T with his flying VVVVVVVVVV: up up and away...

    Yes Scot I am in Florida and the cadaverous governor will veto the will of my Peeps...

    Where you be?

  • California..Where else dude!

  • That's why I'm campaigning so hard for Charlie Crist for Governor - again - this time as a Democrat.

  • Hi Scotty,

    I’ve been using MM for about 5 years now and it has made a big difference. It treats a wide variety of my symptoms effectively with no bad side effects. Just a few:

    a)Tremor - It helps me to relax which lessens tremors, but to really get maximum relief it takes about 2 months of daily use. This according to a Czech study, and I have confirmed this after using much less or little and within 2 months my tremors greatly increased.

    b)depression, motivation - without MM everything is flat. With MM I keep active and motivated all day.

    c)Anxiety – MMM helps me relax. It’s also lessens social anxiety, such as travelling in public when my meds are not effective

    D) Appetite – without MM I have no appetite, with MM I eat and enjoy my food more and will make something with more effort.

    E) Insomnia – helps me to sleep, and If I can’t it helps me relax and do something like read.

    f) relieves distonia

    g) relaxes bladder

    I vaporize my MM. For the last 5 years I have used a HerbalAire with a balloon, but it broke last month and I now use the Plenty vaporizer at home, and the portable Solo when out.

    Generally I vape first thing in the day (with coffee) and every 3 or 4 hours after that. If I’m outside and active I may vape less often. I start the day with a sativa, followed by the strongest indica I have. First high of the day is always the best. If I have a good variety of strains I will us ethem according to my mood and activity. Generally I use sativas during the day to keep my awake and active, and indicas at night when I’m winding down.

    I advocate for MM so feel free to ask any questions...

  • WOW..Great response…A teaching moment…This is the type of reporting that really makes a difference.. Thank you Lethe

  • This is a good video of a talk by a PD neurologist talking about cannabinoids for PD.

  • we do not have medical marijuana in the uk.It helps the symptoms of PD so much and calms down unwanted thoughts but i have to buy it illegally.Its a shame that something that helps so much turns me into a criminal but im willing to do so for the sake of a quality of life.this is my first contact with others like me.

  • Hi David, Welcome to a brave new world and keep the faith, One day I am sure the UK. will see the light and legalize MM. In the meantime call your local leaders and protest this insane policy of making it illegal.

  • Hi David - MM is available in the UK for MS - so there is a precedent but I reckon we would need lots of credible proof before it was considered for Parkinson's. We could try Parkinson's UK but they would need incontrovertible evidence before taking it up o our behalf.

    Could you define exactly what help / relief it provides. Does it address pain ?- I don't know whether it is arthritis or Pd but my fingers and left (my Parkinson's side) big toe are permanently painful. I don't take any tablets since I already take so many but get some relief with Ibuprofin Gel

  • In UK there is a cannabis-based product – Sativex – which can be legally prescribed and supplied in limited circumstances..

    In June 2010 the Medicines Healthcare Regulatory products Agency (MHRA) authorised Sativex as an extra treatment for patients with spasticity due to Multiple Sclerosis (MS). Doctors can also prescribe it for other things outside of the authorisation, but this is at their own risk.

    So in UK it can be prescribed for PD but you need to find a doctor who will do this.

  • I found out that you can bad-mouth MM on UK PD forums as much as you want. But you get booted off if you try and put in a good word....

  • whats the address for the UK. forums?


    I typed "medical marijuana" and got lots of "medical" but absolutely no "marijuana". It's (too) hard to believe that the subject never has come up, rather they are unrelentingly censoring the forum (and information). The medical establishment has their heads in the sand (or heads up their asses) and are part of the problem - not part of the solution....

    If it wasn't for the courts here in Canada we'd have the same repressive small-mindedness.

    Ironically their letter -head on the site says "Parkinson's:

    Change Attitudes"... Hypocrites...

  • Thank you Lethe and Canada rocks, What part of the country are you in?

  • Taw-ra-na Toronto


    More doctors than consumers say medical marijuana should be legal: SurveySurvey

    The legalization of medical marijuana has more support among U.S. doctors than among consumers, a new surveysurvey found.

    The surveysurvey of more than 1,500 doctors and nearly 3,000 consumers found that 69 percent of doctors said medical marijuana can help with certain conditions and treatments. Only 52 percent of consumers expressed that same belief.

    Among doctors, 67 percent said they believed medical marijuana should be a treatment option for patients. Half of those doctors in states where medical marijuana isn't legal said it should be legalized, as did 52 percent of doctors in states considering such laws.


    Play Video

    "Charlotte's Web" strain of marijuana offers hope for children with seizures

    Support for medical marijuana was highest among cancer specialists (oncologists) and blood disorder specialists (hematologists). For those two groups, 82 percent said marijuana can provide real benefits to patients. The same percentage said marijuana should be a treatment option for patients, according to the WebMD/Medscape surveysurvey.

    Among consumers, 50 percent said medical marijuana should be legalized nationwide, including 49 percent of those in states where it is not legal. Forty-five percent said the benefits of medical marijuana outweigh the risks.

    Support for legalization of marijuana for recreational use was lower among both doctors (53 percent) and consumers (51 percent), according to the surveysurvey, titled Marijuana on Main Street.

    Currently, more than 10 states are considering bills to legalize medical marijuana.

    Peer-review research on the benefits of medical marijuana remains limited, the report noted.

    "Despite more than 20 years of anecdotal evidence about the medicinal effects of marijuana, doctors and consumers remain in search of answers," Dr. Michael Smith, WebMD's chief medical editor, said in a company news release.

    "The findings of our consumer-physician surveysurvey indicate the medical community's support for the use of marijuana as a treatment option, particularly among clinical specialties that have pioneered research," Smith said.

    "Yet these surveysurvey data suggest additional studies will inform decision-makers' confidence in where medical marijuana can help and where it might not," he added.

    The surveyssurveys were conducted from late February to early March.

    More information

    The U.S. National Institute on Drug Abuse has more on the medical use of marijuana.

    Copyright © 2014 HealthDay. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.


    Editor’s note: Welcome to Room 420, where your instructor is Mr. Ron Marczyk and your subjects are wellness, disease prevention, self actualization, and chillin’. ~ Steve Elliott

    Worth Repeating

    By Ron Marczyk, R.N.

    I have felt my own mortality and was humbled to learn that two long-time friends my age have been diagnosed with Parkinson’s disease, both within the last few months of each other. My friends, and millions of others, are searching for any new treatment that could heal and restore brain homeostasis and halt the progression of this neurodegenerative disease.

    Cannabinoids are neuroprotectants.

    Worth Repeating: Cannabinoids Stop Brain Inflammation

    We all have fragile friends and family with very similar serious medical conditions whom we all wish we could help. How many times in your private thoughts did think of that person you love and say to yourself, I wish there was a medicine I could find that would heal them?

    When you are searching for hope and it appears, it’s like the hero in a movie appearing in the nick of time. The cannabis plant is that all-around hero of our time.

    “Captain Cannbinoid” aka Captain Cannabis™

    Super powers: Uses cannabinoid power to produce neurogenesis, heal and reset body systems to homeostatic stillness. Sworn to the Cannabinoid Hippocratic Oath to never take a human life.

    The Cannabinoid Hippocratic Oath: As a plant-based medicine I will first do no harm: gentleness is my very nature.


    Patent Title: Cannabinoids act as antioxidants and neuroprotectants


    Assignee: The UnitedUnited States of America as represented by the Department of Health and Human ServicesHuman Servicesarrow-10x10.png

    “As an antioxidant cannabinoids… have a particular application as a neuroprotectants in the treatment of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and dementia”


    What is the significance of US Government Patent 6,630,507? youtube.c...h?v=agZuafXG2Ds

    Helping my friends in their search for evidence-based cannabis treatment, the goldgold standard for evidence appeared in the form of this famous 2003 Department of Health and Human ServicesHuman Servicesarrow-10x10.png medical cannabis patent, which I also learned was a clone of an earlier exact 1998 study by the same researchers.

    Cannabidiol and Δ9-tetrahydrocannabinol are neuroprotective antioxidants/ Proceedings of the National Academy of Sciences / 1998 July


    Cannabis is a potent brain anti-inflammatory medicine

    “The non psychoactive marijuana constituent cannabidiol was found to prevent both glutamate neurotoxicity and Reactive oxygen species -induced cell death. The psychoactive principle of Cannabis, THC, also blocked glutamate neurotoxicity with a similar potency to cannabidiol”. en.wikipedia....e_neurotoxi...

    Taken together, these two studies highlight, document and support what was known for 16 years: that the Department of Health and Human ServicesHuman Services supplied evidence that was vetted for accuracy by the U.S. Patent Office and granted the highest official seal of approval, stating that cannabinoids could be used as a direct form of treatment for the big four neurological diseases — Alzheimer’s, multiple sclerosismultiple sclerosisarrow-10x10.png, Huntington’s disease and Parkinson’s disease.

    As early as 1998, robust evidence existed that endocannabinoids protected the brain from neurodegenerative diseases; the evidence was so good that the U.S. government put a lock on it, for the benefit of U.S. citizens I assume.

    So how come no independent cannabinoid research in the U.S? No first generation cannabis medicines in the pipeline?

    Because of the big lie called Schedule I, which shuts down all positive research.

    This shutdown of scientific research caused direct harm to millions of people who, for nearly two decades, were desperately looking for new treatment options so they could simply live another day. Why no human drug trials?

    “Considering the relevance of preclinical data, the need for finding treatments for motor symptoms that may be alternative to classic dopamine replacement therapy and the lack of efficient neuroprotective strategies in Parkinson’s”…

    “We believe it is of major interest to develop further studies that allow the promising expectations generated for these molecules (cannabinoids) to progress from the present preclinical evidence towards a real clinical application.”

    From: Cannabinoids and Parkinson’s disease /CNS & Neuro. Disorders Drug Targets/Dec 2009


    Dr. Mark Ware on the Endocannabinoid System: youtube.c...h?v=8Jz1nQ_leWE

    “The potential of cannabinoid-based medicines in Parkinson’s have been still scarcely studied at the clinical level despite the existence of solid and promising preclinical evidence…”

    For one government agency to first supply solid evidence that cannabinoids are the new frontier of anti-inflammation brain medicine, then for a second government agency to validate the evidence with a patent, and then for a third government agency to stonewall that same medical research into the development of those drugs that could have been fast-tracked to prevent needless suffering and countless deaths, all for hidden political reasons and in order to not admit that they were

    wrong, is immoral, and the very definition of a crime against the people of this great country.

    Rick Simpson’s Hemp Oil Medicine

    For a government agency to stop patients from accessing life-saving medicine reminds me of another famous experiment conducted when life-saving medicine was withheld from people in the infamous Tuskegee syphilis experiment. Is medical marijuana as Schedule I really any different from this atrocity?


    So, who of those in power for the last 16 years are responsible for stopping real clinical application of medical cannabis research for neurodegenerative disease, and who in power today are stopping this important scientific progress from saving lives?

    Cannabis is nontoxic and has never caused a fatality from direct use, ever! Cannabis is so safe it sets the goldgoldarrow-10x10.png standard against which all other drugs should be measured for safety.

    Trichomes-325x234.pngCan you appreciate depth of that statement and the impeccable safety record of this botanical medicine? The science is on our side, so why not immediate clinical use? The downside of immediate cannabis-based treatments for neurodegenerative disease is near zero, but still no movement towards real clinical application to help average people.

    Schedule I has been falsified and is pseudoscience. en.wikipedia....i/Pseudosci...

    The motor symptoms of Parkinson’s disease result from the death of dopamine-generating cells in the substantia nigra. An unknown inflammation process appears to be killing off these cells; it is here where medical cannabinoids protect the remaining dopamine cells and perhaps stimulate neurogenesis of new ones.

    Pharmaceutical use of cannabis is not new and history shows us how this miracle plant has been misinterpreted through an era of ignorance. Cannabis has been used for thousands of years, and the credibility of marijuana as a therapy specifically for Parkinson’s disease is somewhat new. “Marijuana is a miracle plant that helps Parkinson’s patients and benefits people suffering from many other illnesses,” states PD patient and author of “Marijuana for Parkinson’s Disease ” - Richard Secklin

    OldAgeCannabis.pngMedical cannabis treatment has the potential to help improve function, decrease dyskinesias, delay or stop disease progression, and, most importantly, extend life, preserve function and provide joy.

    Cannabinoids as antioxidants and neuroprotectants, US patent 6630507, are our heroes.

    Here are the top 10 cannabinoid science medical studies that support US Patent 6630507.

    I hope this may be of help to you when formulating your treatment options with your physician.

    1. Endocannabinoid Modulation of Dopaminergic Motor Circuits / Front. Pharmacol. / June 2012


    “There is substantial evidence supporting a role for the endocannabinoid system as a modulator of the Dopaminergic activity in the basal ganglia, a forebrain system that integrates cortical information to coordinate motor activity regulating signals.”

    BrainCannabisLeaf-325x159.png“In fact, the administration of plant-derived, synthetic or endogenous cannabinoids produces several effects on motor function. These effects are mediated primarily through the CB1 receptors that are densely located in the dopamine-enriched basal ganglia networks, suggesting that the motor effects of endocannabinoids are due, at least in part, to modulation of Dopaminergic transmission.”

    “Therefore, it has been suggested that endocannabinoid system modulation may constitute an important component in new therapeutic approaches to the treatment of motor disturbances”.


    According to the Merck Index, 12th edition (the number one reference book for medical doctors), the LD 50 value for rats by inhalation of THC is 42 mg/kg of body weight. Comparing this to an average human being, one estimate of THC’s LD 50 for humans indicates that about 1,500 pounds (680 kg) if cannabis would have to be smoked within 14 minutes.

    “l-DOPA induced dyskinesia (LID) constitute one of the most disabling complications derived from the long-term therapy with l-DOPA affecting up to 40% of PD patients after 5years of treatment”

    “Cannabinoid agonists could exert antidyskinetic effect by regulating glutamatergic release in the striatum and/or by re-establishing endocannabinoid-mediated synaptic plasticity affected by dopamine denervation.”

    2. Prospects for cannabinoid therapies in basal ganglia disorders / Br J Pharmacol. 2011 August


    “Cannabinoids are promising medicines to slow down disease progression in neurodegenerative disorders including Parkinson’s disease and Huntington’s disease two of the most important disorders affecting the basal ganglia. “

    “Cannabinoids like Δ9-tetrahydrocannabinol or cannabidiol protect nigral or striatal neurons in experimental models of both disorders, in which oxidative injury is a prominent cytotoxic mechanism… leads to a slower progression of neurodegeneration in both disorders. This effect would be exerted by limiting the toxicity of microglial cells for neurons and, in particular, by reducing the generation of proinflammatory factors. It is important to mention that CB2 receptors have been identified in the healthy brain, mainly in glial elements and, to a lesser extent, in certain subpopulations of neurons, and that they are dramatically up-regulated in response to damaging stimuli, which supports the idea that the cannabinoid system behaves as an endogenous neuroprotective system. This CB2 receptor up-regulation has been found in many neurodegenerative disorders including HD and PD, which supports the beneficial effects found for CB2 receptor agonists in both disorders…

    “In conclusion, the evidence reported so far supports that those cannabinoids having antioxidant properties and/or capability to activate CB2 receptors may represent promising therapeutic agents in HD and PD, thus deserving a prompt clinical evaluation”.


    3. Medical marijuana treatment for motor and non-motor symptoms in Parkinson’s disease International Parkinson’s Congress/June, 2013 mdsabstra...D=798&id=106491


    “Cannabis holds promise as another treatment option for PD. It can apparently alleviate not only the motor symptoms but also the non-motor symptoms, especially PD-related pain and sleep, thereby improving patient quality of life.”


    4. An overview of Parkinson’s disease and the cannabinoid system and possible benefits of cannabinoid-based treatments /Current Med Chem. 2006 ncbi.nlm....pubmed/17168732


    “Despite the many recent advances in the symptomatic treatment of PD, there is still no realistic prospect for a cure. In recent years, new data support the idea of a relevant role for the cannabinoid system in PD”.

    “As cannabinoids have neuroprotective properties, they have been proposed as potentially useful neuroprotective substances in PD, as well as to alleviate some symptoms in specific circumstances (i.e. parkinsonian tremor associated with over activity to the subthalamic nucleus; levodopa-induced dyskinesia).”

    “Cannabinoid-based compounds might provide protection against the progression of neuronal injury characteristic of this disease; the influence of cannabinoids on local inflammatory events associated with the pathogenesis in PD.”

    “Collectively, all these evidence support that the management of the cannabinoid system might represent a new approach to the treatment of PD”.


    5. The endocannabinoid system as a target for the treatment of motor dysfunction

    Br J Pharmacol. 2009 April ncbi.nlm....pubmed/19220290

    “There is evidence that cannabinoid-based medicines that are selective for different targets in the cannabinoid signaling system (e.g. receptors, inactivation mechanism, enzymes) might be beneficial in basal ganglia disorders, namely Parkinson’s disease (PD) and Huntington’s disease”

    “These benefits not only include the alleviation of specific motor symptoms … but also the delay of disease progression due to the neuroprotective properties demonstrated for cannabinoids.


    6. The Influence of Cannabinoids on Generic Traits of Neurodegeneration / Br J Pharm., Oct. 2013

    “In an increasingly aged population, the incidence of neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease and Huntington’s disease are on the rise. While the etiologies of these disorders are different, a number of common mechanisms that underlie their neurodegenerative components have been elucidated; namely neuroinflammation, excitotoxicity, mitochondrial dysfunction and reduced trophic support.

    Current therapies focus on treatment of the symptoms and attempt to delay the progression of these diseases but there is currently no cure. Modulation of the endogenous cannabinoid system is emerging as a potentially viable option in the treatment of neurodegeneration. Endocannabinoid signaling has been found to be altered in many neurodegenerative disorders…

    Through multiple lines of evidence, this evolutionarily conserved neuro-signalling system has shown neuroprotective capabilities and is therefore a potential target for neurodegenerative disorders. This review details the mechanisms of neurodegeneration and highlights the beneficial effects of cannabinoid treatment.”

    7. The development of cannabinoid CB2 receptor agonists for the treatment of central neuropathies / Cent Nerv Syst Agents Med Chem. 2010 March ncbi.nlm....pubmed/20236042


    “We discuss the role of microglia in the healthy brain, and then the role of microglia in chronic neuroinflammatory disorders, including Alzheimer’s disease and Parkinson’s disease, as well as in neuroinflammation following acute brain injury such as stroke and global hypoxia.

    As activation of CB2 receptor on microglia results in suppression of the proliferation and activation of microglia, there is potential for the anti-inflammatory properties of CB2 agonist to treat neuropathology’s that involve heightened microglia activity.

    In addition, activating CB2 receptors may result in an increase in proliferation and affect migration of NPCs. Therefore, it is possible that CB2 agonists may assist in the treatment of neuropathology’s by increasing neurogenesis.”


    8. The decrease of dopamine D₂/D₃ receptor densities in the putamen and nucleus caudatus goes parallel with maintained levels of CB₁ cannabinoid receptors in Parkinson’s disease

    Brain Research Bulletin/April 2012 ncbi.nlm....pubmed/22421165

    “Our data suggest the presence of an unaltered CB₁R population even in late stages of levodopa treated PD. This further supports the presence of an intact CB₁R population which, in line with the conclusion of earlier publications, may be utilized as a pharmacological target in the treatment of PD”


    9. Functional diversity on synaptic plasticity mediated by endocannabinoids/ ncbi.nlm....les/PMC3481528/


    “To date, the endocannabinoid system is considered the best characterized form of retrograde synaptic transmission. Short-term forms of plasticity induced by cannabinoids have been described in numerous brain areas in different organisms, accounting not only for our understanding of the hippocampus and cerebellum as the major sites of action for endocannabinoid system, but also suggesting that the endocannabinoid system itself is an ancient mechanism in evolutionary terms…

    “However, our more global understanding of the role endocannabinoid system play in regulating behavior and mental disease is just beginning. The endocannabinoid system is thought to be involved in regulating over-excitability and promoting synaptic homeostasis.”



    10. Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson’s disease / Br J Pharmacol. 2011 August



    “Previous findings have indicated that a cannabinoid, such as Δ9-THCV, which has antioxidant properties and the ability to activate CB2 receptors but to block CB1, might be a promising therapy for alleviating symptoms and delaying neurodegeneration in Parkinson’s disease.”


    This post is dedicated to Peter McWilliams.

    Cannabis Is Medicine — Prohibition Does Not Work! Former NYPD cop, former high school health teacher, the unstoppable “Captain Cannabinoid” aka Captain Cannabis, Ron Marczyk, R.N., Toke Signals columnist

    Editor’s note: Ron Marczyk — Captain Cannabinoid — is a retired high school health education teacher who taught Wellness and Disease Prevention, Drug and Sex Education, and AIDS Education to teens aged 13-17.

    He also taught a high school International Baccalaureate psychology course. He taught in a New York City public school as a Drug Prevention Specialist.

    He is a Registered NurseRegistered Nursearrow-10x10.png with six years of ER/Critical Care experience in NYC hospitals, earned an M.S. in cardiac rehabilitation and exercise physiology, and worked as a New York City police officer for two years.

  • You are on a mission and I am right there with you..and just a note to you folks who do not get a full nights sleep, The answer is simple, Medical Marijuana and if this is all it does for you is that not enough for a start..

  • I am my own experiment, I ingest Marijuana every day and I have PD. My opinion is not scientific it is just based on how Marijuana makes me feel. Marijuana is a gift that eases my pain gives me sleep and provides a smooth Sinemet ride into the blood brain barrier helping me absorb more of the meds. My tremor is tamed, My attitude is good and best of all I have had no side effects from, Need I say it again, Marijuana.

  • Hi Scotty I to have had Parkinson for over 10 years, long with reducing my meds . I've taken up physical exercise weights , walking, riding a bike and changed my diet to. But the one thing the meds and everything else is getting a good night sleep. I recently read an article on marijuana use for Parkinson patients there was not one negative issue it was positive results . And in this article they mentioned using it or a sleep study their results were 100% effective . So I thought what hell I'll try it. I did my own study 1). try it after a very busy day and 2). try I after resting all day . Needless to say those 2 times gave me best nights sleep I've had in 10 years! Hope this helps you out.


  • Shaknbacon, Thank you for your response. Cannabis is my sleeping pill, My pain pill and my tremor alleviator. I still have PD and I take Sinemet 3 times a day but physically and mentally cannabis makes me feel almost normal and best off all, No side effects. Spread the word!!

  • Scottyt No thank you for taking that first step in asking this question . I was amazed ,, no overwhelmed by the responses you have received the wealth of knowledge it's almost mind blowing .I have read most of replies and it seems that most hadn't had a bad experience with any side effects at all. versa the side effects from the meds. Have you anyone respond who has had the DBS surgery ?

    I'm on 3 kinds of meds Carbidopa-levodopa 4 times a day, mirapex 3 times a day ,and azilect 1 a day and yes it sucks living your life in 3 hour intervals. But my side effect I have trouble with is my speech . My voice is getting ever so softer and I have to repeat myself almost all the time ,which is very frustrating . I was in voice therapy for about 6 months I stopped because I just couldn't take it anymore.

    Thanks again for being the man who ask the question.

  • I am just a humble messenger doing what I can do for my brothers and sisters who suffer from this terrible disease. I just want to share my own experience and if it resonates with anyone then I cannot ask for anything more. The word Marijuana scares a lot of folks, All I can say is I think your fear is misplaced and as for me, I am going to start using a vaporizer in addendum to my ingesting Hash oil and I will continue reporting my experience with these alternative medicines.

  • Tremor stops and muscles relax within 30 minutes of ingesting with food. Great for sleep. My dr recommended it. Said the only risk is decreased balance. Maintain other meds at first; reduce them very gradually with medical help. Medical cannibas works very well. The only thing it doesn't seem to help is posture.

  • Go to a stretch class for your posture and tell interested parties of your experience with medical Cannabis.Thanks Scotty T.

  • What's the best type and strain of MM for PD?

  • There is Sativa and Indica…PWP do better with Indica heavy cannabis…good for pain, tremors and lack of proper sleep. I use orally at night and vaporize in the daytime….Pot oil…very strong and so I use very little...

  • Eagerly awaiting for legalization in Florida so I can try it for my pain, tremors, and sleep disorder.

  • Medical Marijuana is legal in Florida and has been for 23 years.

  • I've smoked weed 40 years legal or not , Parkinson's for 6 years like it or not. I get medical grade weed and the best that you can obtain for PD is high grade Indica , Sativa has an uppity buzz the former has the knock your ass in the dirt body buzz.

    The benefits are pain and tremor relief , relaxation and sleep, increased appetite . I work full time so I usually do a couple hits at 4:20 , 5:30 do dinner then smoke hits till bed as needed and also use a vaporizer

  • I vape at night before bed, has greatly reduced my muscle cramps and helped my dystonia. I almost feel like i use to pre pd. I use indica, and it really helps. Dana

  • ME TO...

  • It seems it works.

    --- Cannabis and Parkinson Disease

    --- Taylor French BEFORE and AFTER treatments with Medical Cannabis for Parkinson's Disease

    --- Marijuana Documentary - Cannabis Research Studies - 2014

    --- Cannabis Research - Cognitive Dysfunction Inflammatory and Autoimmune Diseases

    --- Medical Cannabis Documentary

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