There had been several posts in the past few months discussing benefits of large doses of coconut oil for relieving portions of PD symptoms. One of the issues that has come up from time to time is the question of the impact of taking a large dose of the saturated fat in coconut oil on one's overall health. I and others have shared comments from doctors reports indicating that their blood work has not shown an adverse reaction to the use of coconut oil in large doses.
We now have found a reference to a scientific study which explains our experiences. A little background: Lauric acid is one of the medium chain triglycerides found in coconut oil. In fact it is the majority constituent, constituting approximately 50% of the medium chain triglycerides in coconut oil. From Wikipedia:
"Lauric acid has been found to increase total cholesterol the most of all fatty acids. But most of the increase is attributable to an increase in high-density lipoprotein (HDL) "good" cholesterol. As a result, lauric acid has "a more favorable effect on total:HDL cholesterol than any other fatty acid, either saturated or unsaturated"; a lower total/HDL cholesterol ratio suggests a decrease in atherosclerotic risk."
 Mensink RP, Zock PL, Kester ADM, Katan MB (May 2003). "Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials". American Journal of Clinical Nutrition 77 (5): 1146–1155. ISSN 0002-9165. PMID 12716665.
 Thijssen, M.A. and R.P. Mensink. (2005). Fatty Acids and Atherosclerotic Risk. In Arnold von Eckardstein (Ed.) Atherosclerosis: Diet and Drugs. Springer. pp. 171–172. ISBN 978-3-540-22569-0.
Much has been written scientific literature regarding the health problems associated with the consumption of saturated fats. Most of these results are based on old research that was conducted prior to the understanding of the distinctions between HDL and LDL. Also missing was the understanding of the different impacts of medium chain triglycerides and long chain triglycerides. Current posts by reputable organizations continue to confuse the issue by referring to the older reports. Since some of these posts have recent dates they give the appearance that current research is having the same findings, when in fact they may reveal that current writers are not keeping up with the field.
Since we are not experts, it is unnerving when the experts become confused. The recent book by Jeff Volek, PhD, RD and Stephen Phinney, MD, PhD.
"The art and science of low carbohydrate living" provides a compelling discussion to support its title. We introduce it here however because it has excellent chapters on the medium chain triglycerides, on the many roles of cholesterol, and how these relate to human health. Most of their claims are carefully documented by references to the scientific literature. This is not light reading, but if you are going to take responsibility for modifying your treatment and your eating habits, you would be well advised to make an effort to understand the pros and cons of the anticipated approach. This book provides many answers.
I personally continue to experience good benefits from my daily 10 T of coconut oil. I have recently reduced my Sinemet from 25/100 3 per day to 1.5 per day VERY GRADUALLY and with medical supervision. So far no adverse reactions and no worsening of PD symptoms.
10T CO = 1200 calories added to my diet. Weight control is an issue. So far I am breaking even, but am feeling a need to make some life-style changes. But PD is a life-style change and so are the long-term consequences of Sinemet. As I consider my options, I crave FACTS. This forum is a wonderful place to share and discuss facts as we find them.