I am on generic sinemet er 25/100mg 6-7 times a day, every 2 hrs and 40 minutes apart while i am awake. Barely walking and swallowing but higher doses gave severe dyskinesia. Severe nausea and vomiting and dizziness and palpitations and severe shortness of breath but my neuro would not switch! Tried mirapex and azilect with side effects and unable to tolerate. Tried to decrease daily doing of sinemet er but if taking sinmet er late than 2 hrs & 40 min. Then i have another set of side effects like severe head pressure and whole body tremor. I have whole body spasm and cramps and electric pain. Need help tapering off!