Amitripyline: Just started taking these for... - Pain Concern

Pain Concern

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Amitripyline

Grannys27 profile image
9 Replies

Just started taking these for arthritis pain and the tiredness in the morning is bad will this get any better as my doctor says take them for at least 2weeks. Not doing much for the pain or the body stiffness yet either. Have come off Co-codamol for Amitripyline.

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Grannys27 profile image
Grannys27
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9 Replies
Cooper27 profile image
Cooper27

I think you do get used to them after a while (I took amitriptyline for about 9 months), but we're all different. Try taking them a little earlier in the evening to see if that helps.

Hzhr7 profile image
Hzhr7

Hi, I'm on amitriptyline too. You need to take it fairly early on in the evening I find. I take twenty milligrams at 7 pm and go to bed between 10&11. I am on pain relief as well. It took me a few weeks to get used to it. Hope this helps xx

shazmill profile image
shazmill

Hi there. They can take awhile before you feel any improvement. I take 75 mg on a evening between 6.30 -7pm. At 10 or 11pm they kick in

cyberbarn profile image
cyberbarn

My son started on 10mg and found it took a couple of weeks to adjust. But amitriptyline only works for about 1 in 3 people. you do need to give it a couple of weeks though to see if it works for you, so keep going!

Tig387 profile image
Tig387

Hi Grannys27, I'm in my 2nd week of taking amitriptyline started at 25mg working my way to 50mg in 5mg stages each week. I too am tired in the mornings, in fact all day really but each 5mg seems to get easier. It hasn't helped my pain yet but hoping it will when it gets in my system more as well as the stronger dose. What dose are you taking?

Sheila-Squirrel profile image
Sheila-Squirrel

Hi there. I’m on 75mg of amitriptyline, tramadol, gabapentin and co-codamol for pain relief. I liken the effects of the amitriptyline to feeling hungover without having the pleasure of a drink. I initially had brain fog till the middle of the day. Changing the time I took it to early in the evening helped. I worked backwards from my bedtime to find the earliest I could take it with knocking myself out before going to bed. Everyone reacts differently so it’s a trial and error thing. Hope things settle down for you soon.

mmb50 profile image
mmb50

I was on Amitriptyline for a number of years to help with Fibromyalgia and it helped greatly. I did suffer ‘hangover’ but took it earlier, around 8pm went to bed about 11 pm and that did help to feel better in morning. I stopped in April 2016, was diagnosed with RA in May 2017 after months of dreadful pain. Was taking usual anti inflammatories and tramadol, paracetamol and eventually started back on Amitriptyline to help me sleep. (I also take co-codamol) It works well for me and after couple of weeks I had no hangover. Like earlier reply we’re all different so can only go by my own experience. I really hope you get some benefit and feel better in the mornings. 🙏

jackie40luke profile image
jackie40luke

i'm on Amitriptyline and Zapain and im still in pain, i was put on Amitriptyline for stabbing pains in my hips, i still get them they are meant to relax your muscles but not been doing owt for me , they make me tired which probably means making me relax x good luck x

Purple001 profile image
Purple001

Hi, I've recently just started off on amitriptyline too. I'm on my second week. I was the same, the first few days I could barely move I was so weak but by about day 3 I gradually improved, im on week 2 now and the tiredness has reduced alot! Like already mentioned try take it as early as you possibly can. I take it at 7pm each night. Everyone reacts differently to medications but I would give it more time if you can but you know your body best so whatever you think! I was also told it can take a month for it to work as it has to build up in your system. Hope it works out for you xx

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