Trial

[govanhill]

Hi all. I am about to start the Sierra trial. It is anew drug with Gemcitabine. Wondered if anyone else was on this. Thanks Morag

[Katmal-UK]

Hi Morag. Not heard of that trial. What's the drug called - or is it called Sierra?

[January-2016-UK in reply to Katmal-UK]

I think it’s probably the same trial as Gina had just started, SRA-737.

[govanhill in reply to January-2016-UK]

Yes that is it. Couldn't remember. Do you know how Gina is doing on it?

[January-2016-UK in reply to govanhill]

I think she’s only had the one Gem on Monday and then the trial drug on tues and wed. I’ll see her on Monday when she has Gem again and ask her to let you know how she’s feeling, unless she comes on line before.

[govanhill in reply to January-2016-UK]

That's great. Thanks for that. Morag

[Yoshbosh]

I’ve signed the pre-trial consent forms, but haven’t heard anything yet. I’m currently on weekly taxol, so signing up now is a speculative ‘if/when I need it in the future.’ Good luck with it.

[govanhill in reply to Yoshbosh]

Thanks. Think I am starting on the 9th January. Quite a few tests first. Morag

[jane2014]

Hello Morag, I just signed the paperwork for this trial today so hoping to start it as soon as possible. Hope it goes well for you and do keep in touch. Jane x

[govanhill in reply to jane2014]

Hi wondered how you were getting on with the sierra trial. I started about 3 weeks ago. It is taking quite a lot out of me. Morag

[jane2014 in reply to govanhill]

Hello Morag, I think I’m a wk ahead of you so I haven’t had any treatment this week which has been such a relief. Im sorry to hear it’s taking so much out of you. I too have found it draining. I ended up in A&E in the second week with a high temperature. Although I stayed in for 3 days they couldn’t identify what the problem was.

In general, my platelets and bloods have been low and they put me on magnesium and iron to help but I remain lacklustre. I wish they would do a CA125 reading so I could at least see if it’s working. I won’t know until my scan on 11th March. I really have no sense of how effective or not it is.

Hopefully you will have a week without treatment to recharge your batteries.

Best of luck, Jane x

[govanhill]

Hi. I had to miss a week of treatment and have the dose lowered as I felt absolutely exhausted for nearly a week. Also had the runs for a few days. Sounds like you have had sometroublestoo. Not sure what my ca 125 is either. I k ow I am a bit anaemic. On magnesium too.Hope thingsimprovefor us both. Morag.

[jane2014 in reply to govanhill]

Hello Morag,

I too was anaemic and magnesium deficient, and I had another stint in hospital with high temperature. Again, they couldn’t pin point the cause but they delayed treatment a week as I was on holiday in Italy last week and they didn’t want to risk a high temperature whilst I was there. My CA125 has shot up to over 1000 but they are continuing with treatment as scan shows borderline progression which means it is 20% or less.

Hope things are working out better for you.

Jane x

[govanhill]

Hi I am hospital just now. Had treatmemt on Wedneday felt terrible by Friday. Temp was high and had raised infectionmarkers. On iv antibiotics. Not sure if I will get treatment on Wednesday. Consultant said only if markers come down. Glad you managed a holiday. Morag

[jane2014 in reply to govanhill]

Sorry to hear you’re in hospital. Sounds like the high temperature could be a side effect of this treatment if we’re both getting it. My nurse today mentioned someone else on the same regime had experienced it too. Hope you get out soon and are comfortable in the meantime.

Jane x

[govanhill in reply to jane2014]

Thankyou. Will keep in touch. Good to compare notes. Morag