Anti inflammatories: Good morning. In bed post... - My Ovacome

My Ovacome

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Anti inflammatories

Sh-x profile image
Sh-x
34 Replies

Good morning.

In bed post op long lies, just googling as you do.

News today on canakinumab very interesting.

Thought it might be of interest to some of you too.

Shona

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Sh-x
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34 Replies

Hi Shona I saw this on a fb feed but didn't know what the drug is or if widely used.

RonLitBer profile image
RonLitBer

reuters.com/article/novarti...

in reply to RonLitBer

Thank you

Sh-x profile image
Sh-x

It was the anti-inflammatory title on the article that caught my eye. I've read with great interest drdu's posts discussing the benefits of Ibuprofen and researched various articles of the same vein. There's obviously something.....As they say ibuprofen being a cheap drug doesn't encourage research. Lots of lifesaving drugs are found by accident.

Shona

drdu profile image
drdu in reply to Sh-x

Having read the Reuters article just now this is not an anti-inflammatory related to ibuprofen etc . But interesting. Ibuprofen etc can kill cancer cells in some people when the cancer already well controlled. It is a direct effect on cancer cells.

E xx

Eriksendi profile image
Eriksendi

Article in the Daily Mail here in UK today on same drug. Talking about a breakthrough in dealing with heart disease and also used for treating lung cancer.

eileen_alberti profile image
eileen_alberti

I've been on naproxen [anti-inflammatory] for years and now am in stage 3 chronic kidney failure. First thing doc told me, not one more pill. I'm still using Zeluja for the ovarian. It's been a rough 10 days.

On the bright side I finally moved [after 11 months] and sis & b-in-law helped me get so many things done, God love them. So I do have the happiness factor.

We had 4 day rain in Sarasota, Fl and it measured 21 inches. I now have lake front property! But I don't have a boat. Maybe I can make one out of the big box in the garage.

Blessings to all, Eileen

greenpink profile image
greenpink in reply to eileen_alberti

Gosh, you're coping with a lot. Did the Naproxen cause the kidney failure? Hope the lake subsides. I've been following the hurricane & storm in the US & the floods in Asia. Looks scary. I moved in June to a ground floor property, no more living on third floor of a block with no lift. Started third line chemos yesterday and was able to walk into new block off the road. Great. Happiness factors help, my partner and family. Two year old nephew makes me laugh. Good luck

eileen_alberti profile image
eileen_alberti in reply to greenpink

Doc says napronen caused kidney failure. I've probably been on it for, wow, thinking back, 20 years. Discussing these things helps arrange your brain.

The lake is gone, sunshine for rest of week. I don't have flood insurance. Scary. Everyone said no problem here. I think that there are 2 million people that thought that, then came Harvey. So sad.

So your happiness factor is you don't have to lug groceries up 3 flights. See, we don't ask for much. Let me take this opportunity to finally shut up. And anyway, I have more pictures to hang. I feel better now that I got all this off my chest. Interesting name you have. All the best of everything to you, Eileen

eileen_alberti profile image
eileen_alberti in reply to eileen_alberti

house looking better every day. hanging pictures that have been under bed for years. Good distraction from pain.

Sh-x profile image
Sh-x

Hi Eileen.

Thanks for reply.

I have always had a gut feeling that anti-inflammatories would somehow have part in a cancer prevention/cure and tend to pick up on any research. I must admit though, as yet I have been to sceptical to take, especially during treatment.

Your new home sounds fabulous and will be so nice now your in to tinker around making it yours.

I am very lucky that I found my forever home after my second child was born 24 years ago, still tinkering though.

xx Shona

drdu profile image
drdu in reply to Sh-x

PS don't be sceptical. The evidence is in peer-reviewed medical articles. But anti-inflammatory drugs are weak anti-cancer drugs and don't work well unless you are in remission and don't work for all, one paper suggesting 50%.

E x

in reply to drdu

I've been interested in your posts over the years and did take aspirin for a while until I got hit with simultaneous H Pylori and bowel obstruction! Both now hopefully dealt with. Now.... in medical terminology I suspect that "stable disease" is not the same as "in remission"... and that therefore there would be little point in me going anti-inflammatory again...Correct?

Beautiful morning in London. I hope it is where you are. x

drdu profile image
drdu in reply to

I think it may well help to some extent in stable disease. Worth a try. Thanks, glad to have helped. Walking in Italian dolomites just now, marvellous.

Best wishes.

Eileen xx

in reply to drdu

Lucky you... sounds wonderful... I'm pounding the pavements getting in training for the Target OC walk - not quite the same thing!

drdu profile image
drdu in reply to

Good luck with the walk xx

drdu profile image
drdu

Yes I wouldn't recommend taking an anti inflammatory during chemo. Yes kidney failure is a small risk with taking an anti inflammatory long-term but many people take them long-term with no problems e.g. those with rheumatoid arthritis.

Best wishes

Eileen xx

Sherrym profile image
Sherrym in reply to drdu

Hi drdu, is 75mg aspirin ok or should I switch to ibuprofen? Still dormant at around 20 months now

drdu profile image
drdu in reply to Sherrym

I think 75mg aspirin as good as ibuprofen. Glad all going well. All best wishes.

Eileen xx

eileen_alberti profile image
eileen_alberti in reply to drdu

I have osteo arthritis and was on methotrexate for that. Add anti-inflamatories but never got any relief. I'm drug sensitive so other were out. I feel that the real problem the whole time was the ovarian. You don't get to stage 4 overnight. It took changing primary's 3 times in 3 years [and what a pain that is] that got me to the diagnosis. Emotional side is docs look at you like you have 3 heads and are a chronic complainer. Well, hell yes, you try living in this condition for 3 years while you're begging for help. Neatest wrinkle: can't pee. Stenosis can cause that so 9/15 seeing neurology. Hope I can pee in the mean time.

I read thru this to check for typos and thought "she's really on a rant". I hope I didn't hurt your brain.

Blessings to all, Eileen

drdu profile image
drdu in reply to eileen_alberti

That sounds a nightmare Eileen. Fair enough to let us know. Good luck on 9/15.

Love

Eileen xx

drdu profile image
drdu

PS again! Am retired gp as well as ovarian cancer patient , and so have some idea of what I am talking about. The anti cancer effect of anti-inflammatory drugs has been known in research for a long time.

E x

greenpink profile image
greenpink in reply to drdu

Hi drdu,

I have read your posts about ibuprofen and aspirin for a few years now. I took 75 mg aspirin during two remissions --- mostly during the second remission. My oncologist told me that aspirin prevents colon cancer and my BRACA 2 doesn't increase risk of colon cancer. She didn't think it of benefit to Ovarian cancer. I started third line treatment yesterday, Gem Carbo, she said I could still take 75 mg of aspirin, but not if my platelets become low -- risk of bleeding

drdu profile image
drdu in reply to greenpink

I did a reply to this 5 mins ago but it has disappeared ! Basically some oncologists don't seem well-informed about these drugs. My own oncologist only admitted to me a year ago or so that they have an anti-cancer effect. But as said before they don't work for all. But it is a general effect against all cancers apparently. See the articles I have quoted in past.

All best wishes.

Eileen xx

greenpink profile image
greenpink in reply to drdu

Thanks Eileen. I have been grateful for what you have posted over the years and your experiences. My two ovarian recurrences have both been cancerous cysts on my sigmoid colon/rectum area and so my oncologist is confused, thinking I'm taking aspirin to prevent colon cancer, instead of ovarian (at least I think that is what she thinks!). I'm aware they don't work for all. I think the research and your posts have and continue to be very helpful. Thanks

drdu profile image
drdu in reply to greenpink

Thank you greenpink.

Love E xx

eileen_alberti profile image
eileen_alberti in reply to greenpink

Lynch Syndrome, a high family history of colon cancer. ovarian cancer seems related. Did my colonoscopies for 35 years. Had many polyps removed. I was a good girl. Was to gastro 3 times in 3 years complaining about symptoms. He never mentioned Lynch. HHMMMM........

drdu profile image
drdu in reply to eileen_alberti

They ought to have thought of lynch syndrome or mentioned it to you.

E x

eileen_alberti profile image
eileen_alberti in reply to drdu

Well, where did I go wrong?

eileen_alberti profile image
eileen_alberti in reply to drdu

We should compile all this into a book so we can get on TV & announce to the world about ovarian cancer and fight for some research. I'm doing my one on one info. but it's a slow go. blessings to all, Eileen

drdu profile image
drdu in reply to eileen_alberti

Thanks Eileen. All best wishes.

Love

E xx

Sh-x profile image
Sh-x

Hi Eileen(drdu)

Thanks for your response. I most likely will start on ibuprofen when finished chemo as it has always been popping up randomly in articles since I was diagnosed and I believe in gut instinct.

Cheers Shona

drdu profile image
drdu in reply to Sh-x

All best wishes Shona. Thinking of you. It is a hard road, isn't it? Good luck

E xx

eileen_alberti profile image
eileen_alberti in reply to Sh-x

Gut instinct: your best friend. Never ignore it.

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