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Olaparib
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BRCAAWAY Trial: Abiraterone and Olaparib work way better together than sequentially in mCRPC for BRCA1/2 and ATM
So this is over three years median compared to the abiraterone arm, which was about eight and a half months, and then 14 months for the
olaparib
. " https://www.urotoday.com/video-lectures/asco-gu-2024/video/mediaitem/3865-brcaaway-trial-impact-of-abiraterone-and-
olaparib
-combination-in-prostate-cancer-maha-hussain.html
So this is over three years median compared to the abiraterone arm, which was about eight and a half months, and then 14 months for the
olaparib
. " https://www.urotoday.com/video-lectures/asco-gu-2024/video/mediaitem/3865-brcaaway-trial-impact-of-abiraterone-and-
olaparib
-combination-in-prostate-cancer-maha-hussain.html
Maxone73
in
Advanced Prostate Cancer
2 months ago
lynparza / olaparib
hi everyone- my dad had progression to chest wall and his hip on ibrance after about 14 months on it so he switched to lynparza/
Olaparib
for MBC in October of 2023. He had a pet scan on 1/29 that showed a complete metabolic response.
hi everyone- my dad had progression to chest wall and his hip on ibrance after about 14 months on it so he switched to lynparza/
Olaparib
for MBC in October of 2023. He had a pet scan on 1/29 that showed a complete metabolic response.
Jenniferp2122
in
SHARE Metastatic Breast Cancer
2 months ago
conflict of opinion
Am on Avastin and
Olaparib
. My CA125 is slowly decreasing but I am still somewhat concerned by the differing opinions x
Am on Avastin and
Olaparib
. My CA125 is slowly decreasing but I am still somewhat concerned by the differing opinions x
Beaver54
in
My Ovacome
15 days ago
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How long has Olaparib worked for you?
I've been on
Olaparib
for 20 months and my PSA has dropped from 10 to 1.5. It has started to rise again and is now 4.2. I'm BRCA2 mutation. I'm wondering how long
Olaparib
has worked for other people. Thanks.
I've been on
Olaparib
for 20 months and my PSA has dropped from 10 to 1.5. It has started to rise again and is now 4.2. I'm BRCA2 mutation. I'm wondering how long
Olaparib
has worked for other people. Thanks.
davebliz
in
Advanced Prostate Cancer
5 months ago
How active were/are you with Olaparib (Lynparza)?
I started
Olaparib
today. I am supposed to start work at 40% 1st of May, and increase by 20% each month. I know that I could have some side effects with
Olaparib
, I would rather
NOT KNOW
so much about them as psychologically I usually develop all symptoms I think I should have.
I started
Olaparib
today. I am supposed to start work at 40% 1st of May, and increase by 20% each month. I know that I could have some side effects with
Olaparib
, I would rather
NOT KNOW
so much about them as psychologically I usually develop all symptoms I think I should have.
IsaStarr
in
My Ovacome
29 days ago
Olaparib Combo Improves PFS/Responses in Metastatic CRPC - from ASCO GU2024
https://www.cancernetwork.com/view/
olaparib
-combo-improves-pfs-responses-in-metastatic-crpc
https://www.cancernetwork.com/view/
olaparib
-combo-improves-pfs-responses-in-metastatic-crpc
Maxone73
in
Advanced Prostate Cancer
3 months ago
Finishing Olaparib PARP after 2 years
I just wondered if any of you could share your experiences after ending
Olaparib
or another PARP. Have you had a recurrence or have you stayed NED?
I just wondered if any of you could share your experiences after ending
Olaparib
or another PARP. Have you had a recurrence or have you stayed NED?
Carpediem68
in
My Ovacome
18 days ago
2 months on Olaparib and my CA125 has risen
I started taking
Olaparib
about 2 months ago. The first month was pretty rough but the second month much better. When I started
Olaparib
, my CA-125 was 19 about 5 weeks after my 6 rounds of chemo after being in remission for about 6 years.
I started taking
Olaparib
about 2 months ago. The first month was pretty rough but the second month much better. When I started
Olaparib
, my CA-125 was 19 about 5 weeks after my 6 rounds of chemo after being in remission for about 6 years.
Chanterelle
in
My Ovacome
2 months ago
Heading down hospice road too…
Next step was Lynparza (
olaparib
), started January 5 which left him a zombie, unable to eat, drink and it severely dropped his hemoglobin. He ended up in the hospital after 3 weeks on it for a blood clot in his leg and blood transfusion so
olaparib
was stopped.
Next step was Lynparza (
olaparib
), started January 5 which left him a zombie, unable to eat, drink and it severely dropped his hemoglobin. He ended up in the hospital after 3 weeks on it for a blood clot in his leg and blood transfusion so
olaparib
was stopped.
LJGD
in
Advanced Prostate Cancer
1 month ago
Olaparib for Metastatic Castration-Resistant Prostate Cancer With BRCA1 and/or BRCA2 Alterations
RESULTS
Olaparib
was associated with longer rPFS (hazard ratio [HR], 0.22 [95% CI, 0.15 to 0.32]) and OS (HR, 0.63 [95% CI, 0.42 to 0.95]) than control.
RESULTS
Olaparib
was associated with longer rPFS (hazard ratio [HR], 0.22 [95% CI, 0.15 to 0.32]) and OS (HR, 0.63 [95% CI, 0.42 to 0.95]) than control.
Balsam01
in
Advanced Prostate Cancer
4 months ago
Gastric discomfort with Olaparib
I’m currently taking 300mg of
Olaparib
per day and am experiencing gastric discomfort and feelings of … .Wanting to burp but nothing happens .Something lodged in my food pipe (there isn’t and no problems with swallowing) . .
I’m currently taking 300mg of
Olaparib
per day and am experiencing gastric discomfort and feelings of … .Wanting to burp but nothing happens .Something lodged in my food pipe (there isn’t and no problems with swallowing) . .
Alfiepop
in
My Ovacome
1 month ago
Olaparib and Radium 223 synergy ?
I seem to recall seeing that there was a trial on seeing if there was synergy to taking
Olaparib
and Radium 223. But can not find it. Anyone have any knowledge of this? I'm BRCA2 mutated and currently taking
Olaparib
, and considering Radium 223. Thanks.
I seem to recall seeing that there was a trial on seeing if there was synergy to taking
Olaparib
and Radium 223. But can not find it. Anyone have any knowledge of this? I'm BRCA2 mutated and currently taking
Olaparib
, and considering Radium 223. Thanks.
davebliz
in
Advanced Prostate Cancer
6 months ago
Enlarged pelvic lymph node
Has anyone received surgery/radiotherapy for an enlarged pelvic lymph node and still been receiving
Olaparib
along side this? Sending best wishes Lisa
Has anyone received surgery/radiotherapy for an enlarged pelvic lymph node and still been receiving
Olaparib
along side this? Sending best wishes Lisa
Alfiepop
in
My Ovacome
5 months ago
starting on niraparib after frontline chemo
I’m stage 3A HGSOC and HRD+ BRCA negative and I’ve been reading quite a few posts that
Olaparib
seems to be mentioned more in connection with HRD+ so I’m just wondering if any of you lovely ladies can enlighten me further on this. Thanks x
I’m stage 3A HGSOC and HRD+ BRCA negative and I’ve been reading quite a few posts that
Olaparib
seems to be mentioned more in connection with HRD+ so I’m just wondering if any of you lovely ladies can enlighten me further on this. Thanks x
Schnauzer19
in
My Ovacome
3 months ago
RSI type symptoms to wrists and thumbs
Had severe hyposensitivity reaction to docetaxel so looking at
olaparib
subject to gene testing. Coming off prednisalone gradually. Interested if anyone experienced similar issues with wrists and how long it lasted.
Had severe hyposensitivity reaction to docetaxel so looking at
olaparib
subject to gene testing. Coming off prednisalone gradually. Interested if anyone experienced similar issues with wrists and how long it lasted.
FortyWinks
in
Advanced Prostate Cancer
21 hours ago
Olaparib side effects
Just looking to hear from anyone who might be having side effects with
Olaparib
I have been taking 300mg a day for almost 18 months. It’s been very tolerable until a few weeks ago. Started with shoulder pain but now every joint and muscle hurts ( especially first thing in the morning).
Just looking to hear from anyone who might be having side effects with
Olaparib
I have been taking 300mg a day for almost 18 months. It’s been very tolerable until a few weeks ago. Started with shoulder pain but now every joint and muscle hurts ( especially first thing in the morning).
Mysticmeg123
in
My Ovacome
5 months ago
Which treatment option best for recurrent oligo?
no toxicity from the PARPi). 7
Olaparib
+ Abiraterone.
no toxicity from the PARPi). 7
Olaparib
+ Abiraterone.
Purple-Bike
in
Advanced Prostate Cancer
2 months ago
Leo 2327
Hi to all the ladies on this journey I am 3c ovarian cancer since May 2022 had 8 lots of chemo and debulking surgery and stoma then been on avastin for over a year last one next Friday and also take
olaparib
I am NED at the moment but I am suffering realy bad with hot sweats and tiredness is anyone else
Hi to all the ladies on this journey I am 3c ovarian cancer since May 2022 had 8 lots of chemo and debulking surgery and stoma then been on avastin for over a year last one next Friday and also take
olaparib
I am NED at the moment but I am suffering realy bad with hot sweats and tiredness is anyone else
Leo2327
in
My Ovacome
3 months ago
PROpel Maintains Efficacy of Olaparib/Abiraterone in mCRPC
https://www.targetedonc.com/view/os-analysis-of-propel-maintains-efficacy-of-
olaparib
-abiraterone-in-mcrpc
https://www.targetedonc.com/view/os-analysis-of-propel-maintains-efficacy-of-
olaparib
-abiraterone-in-mcrpc
Maxone73
in
Advanced Prostate Cancer
7 months ago
Olaparib hasn’t worked for me . Anyone had this happen and had success with another PARP?
This is just a year after 1st recurrence, Chemo reduced cancer to nearly NED, 7 months of
Olaparib
and then CT scan showed new tumour on spleen. CA125 36. Oncologist mentioned later trying another PARP possibly Rucaparib. Anyone had success when one didn’t work ?
This is just a year after 1st recurrence, Chemo reduced cancer to nearly NED, 7 months of
Olaparib
and then CT scan showed new tumour on spleen. CA125 36. Oncologist mentioned later trying another PARP possibly Rucaparib. Anyone had success when one didn’t work ?
Towergirl
in
My Ovacome
3 months ago
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