I was originally diagnosed T3 N1 M0 in May, had 3 cycles of EOX chemo and then the Ivor Lewis op 9 weeks ago. Operation went well but discovered quickly afterwards that the "gold standard" procedure of pre op chemo has failed massively in my case.
Pathology tests after the op showed that the chemo did not work. (Interesting to note that the re-staging CT scan at the end of chemo implied that there was a significant radiological response to the chemo!!)
In my case, the "gold standard" effectively let the cancer remain "untreated" in my body for the 15 weeks between diagnosis and operation. And as a result, I've recently found out that I now have secondary liver cancer.
I had heard that a reasonable percentage of people don't respond the the chemo pre op - but was wondering if anyone knew of any study results which showed percentages - or alternatively the percentages of people who do respond positively to the pre op chemo.
Just a pity there's no test available yet in this country to identify the group of people like myself who would presumably benefit greatly by going straight to the operation.
I'm now on my first cycle of Cisplatin, 5FU and Herceptin and slowly coming to terms with the change in prognosis.
All the best.