Low wbc

[Lamc]

WBC is low , been on methotrexate for a couple of years with no real issues until now. Is methotrexate likely to be the cause??

[Hidden]

Are you taking any other DMARDS or Pred? MTX can cause lowered WBC as can all DMARDS. So it is most likely the cause. If your rheumy team think is a concern, they will either lower the dose, or ask you to stop using it for a short while. Perhaps you should ring them to ask what measures they want to take. Or ring the NRAS helpline Opening times: Monday to Friday, 9.30am - 4.30pm 0800 298 7650

[Lamc in reply to Hidden]

Only on methotrexate. Thanks for your message, will speak to gp later today with luck

[Hidden in reply to Lamc]

GP won't know, you need to talk to rheumy or rheumy nurse.

[nomoreheels]

Could be a sign of an infection. A dipstick test should be done. I'm on MTX & had this happen, it can cause a dip. Best to let your Rheumy Nurse know as even if you don't feel ill it needs checking out.

[sparklyshazza in reply to nomoreheels]

Raised wnc are a sign of infection not low

[nomoreheels in reply to sparklyshazza]

Generally, more commonly, yes, but a viral infection such as flu or more serious infections can result in a dip so shouldn’t be dismissed.

[Mmrr]

Can I ask who took your blood and told you your WBC was low, and did they offer any advice ? They should have done.

My WBC has been low throughout my experience with RD. But until starting baricitinib I have not had any problems with infections. So don't worry too much, but do ask for advice from rheumatology.

[Lamc in reply to Mmrr]

Bloods are checked monthly at gp (shared care between gp and consultant) so low WBC showed up in routine bloods. I feel well and joints all good just now, so reluctant to reduce methotrexate (on 15mg) . Decision is to recheck bloods in 2 weeks.

[sparklyshazza]

If its the neutrophils then stop mtx and repeat bloods one week... wbc low is different. Ask what is low specifically