I inject methotrexate on a Wednesday evening and don’t want to change my day because of my working days... BUT, I accidentally took my folic acid dose this morning... which of course I don’t normally take on methotrexate day.... should I inject anyway, or miss the dose altogether? Not too sure what the impact is.... no use phoning advise line as 1. It would be in the morning and 2. They are short staffed and not responding to queries and ansaphone refers you back to GP. Thoughts please?
Oops folic acid on methotrexate day...: I inject... - NRAS
One reason they may take folic acid on MTX day is it's only a 1mg dose so wouldn't affect the efficacy by much at all. I do wonder though how much use such a low dose is in helping side effects & if it's why leucovorin (folinic acid) is prescribed in the US, less so in the UK? Not sure if 5mg doses of FA are available there.
You've probably decided what's best for you by now but just to add my experience... I've been on MTX 10 years so in that time not surprisingly have done this myself, no ill effects so I wouldn't worry about not injecting the same day. If you're bothered though you could for once inject tomorrow, not take your folic acid & then inject again as normal on Wednesday next week, done this if I've had to miss injecting on Wednesday (my day too, mornings though). You'll be fine either way.
Good, that's what I've done before. You're correct, it can reduce the effect of MTX but it's minimal when compared to your dose, still best not to do it if our Rheumy's request we don't! By the way I said you could inject tomorrow, I of course should have said the following day (which would have been Thursday), I was late replying to your post.