Sulfasalazine : Hi everyone. What are yr thoughts on... - NRAS

NRAS

36,426 members45,076 posts

Sulfasalazine

jaqi1 profile image
17 Replies

Hi everyone. What are yr thoughts on sulfasalazine please

Written by
jaqi1 profile image
jaqi1
To view profiles and participate in discussions please or .
Read more about...
17 Replies
14bubbles profile image
14bubbles

My personal experience of sulfasalazine is mostly negative unfortunately, but this was down to my body not tolerating it well, it caused me a lot of problems with my immune system and after trying several times to build up to the maximum dose, I never actually managed it without it sending my immune system haywire. As far as I am aware, it was not a common reaction and other people are fine with it. All that being said, I believe it did improve my symptoms for the time when I was taking it, so I wish I could tolerate it!

dembonesDAMNBONES profile image
dembonesDAMNBONES in reply to 14bubbles

I hear you on the immune angle.

RA, OA, Fibromyalgia and Emphysema.

It's no fun, when the Sulf knocks your immune system about.

I can't take any of the alternatives, so I'm stuck with it, however, rather than taking 500mg five times a day I take them all at once and find this a lot more tolerable, as I have one bout of nausea, then I can get on with the rest of my day and my Rheumy and GP are happy with this arrangement.

Fighting4me_17 profile image
Fighting4me_17 in reply to 14bubbles

Really saddened for gou

wishbone profile image
wishbone

Sulfa was my very first med. Not on it for long though as I soon developed what looked like an insignificant rash but had to come off it.

Mmrr profile image
Mmrr

Sulpha initially helped me, but I developed an allergy to the salicylic acid component and had to stop taking it.

Sheenadon594 profile image
Sheenadon594

I was diagnosed with RA in 2004 & given sulphasalazine. I had no problems at all & eventually went into remission & was discharged. Unfortunately after 6/7 years it has reared its ugly head again & I,ve just started the process all over again. It worked for me last time & am confident it will do the same again.

mccaffs2014 profile image
mccaffs2014

I have been on Salazopyrin for over two years. I had no serious side effects,dry skin, infected nasal tissue,yellow wee. Unfortunately it is now ineffective and I am waiting for a new treatment

sylvi profile image
sylvi

I was on sulpha for years when consultant took me off that and hydroxy as he wanted me on a new drug and it had to clear my system, but there have been complications and I am still without any drugs apart from MTX and painkillers. I have to say I did very well on the drug with no side effects.xxxx

Rafandready70 profile image
Rafandready70

I had it added in with MTX and hydroxychloroquine and it really helped with chronic knee pain and swelling . I’m now on Benepali though so don’t take it anymore.

sunnyweek profile image
sunnyweek

I have taken sulphasalazine for about 27 years, four tablets a day, I couldn't tolerate six a day, so reduced back to four. No known side effects in that time except yellow urine.

Happygranny1958 profile image
Happygranny1958

I am on sulphasalaziine and methotrexate. I also cannot tolerate six tablets a day and have reduced down to three.

beeckey profile image
beeckey

I felt realy unwell on it lost nearly 2 stone very quickly but i know lots of people do very well on it but my body could not tolerate it.Hope you can get results with it,

dbestdeb profile image
dbestdeb

I was on it for a couple of years and had no issues except heartburn. It helped the pain but not the fatigue. Make sure you take it during a big meal to avoid stomach upset.

dembonesDAMNBONES profile image
dembonesDAMNBONES in reply to dbestdeb

I'm on Omeprazole to combat any adverse effect to the stomach and it also helps with taking Naproxen, as that, too, can tear the stomach lining.

Uga35570 profile image
Uga35570

Sorry to be negative but my stomach couldn't tolerate sulfa nor could I tolerate mxt and hydroxy tablets so now am on mxt by injection much better. Hope it all goes well for you whatever med you have in the end.

Paulajolo profile image
Paulajolo

Made me very ill. Severe rash which took 6 months to clear and referral to Dermatology. Only took 4 tablets.

2 years ago now. Worst reaction to medication I've ever had.

Hobbits profile image
Hobbits

My current biologic isn’t completely effective so my Rheumy tried me a second time on Sulphasalazine. Like the first time, really bad nausea and constant migraines. My boss found me in the lunchroom sitting in the dark. She offered me a Motrin. Bad mistake, resulted in heart palpitations. Sulphasalazine is a no go for me. I wish I could take this drug as it’s one of the least harmful ones I hear.

You may also like...

sulfasalazine or leflunomide

so know I need something else. I’d like some idea what to expect from these and if one may be...

Sulfasalazine and depression

anyone has any experience or knowledge about sulfasalazine and depression? I have a history of...

Sulfasalazine shortage

if anyone else is struggling to source their sulfasalazine medicine. Told yesterday there is a...

Benepali with sulfasalazine

else on weekly 50mg benepali EpiPen plus 3g sulfasalazine a day?Start my benepali next Tuesday with...

Sulfasalazine questions :)

treatment a few months ago. I was started on Sulfasalazine and worked my way up to 4 pills a day. I...