Does Sulfasalazine work?: Hello! I have RA and I am... - NRAS

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Does Sulfasalazine work?

bmarty
bmarty

Hello! I have RA and I am currently on methotrexate, plaquenil, mobic, and most recently sulfasalizine. I also take prednisone when I have a flare. I have only been on the sulfasalazine for approx one month, 2 pills daily. I am just now able to take this medication without it causing extreme acid reflux and stomach upset. However, I can't tell it has helped with any of my pain. Is this a low starting dose and has anyone else had good luck with sulfasalazine? Also, how long should I expect it to take before I see any possible results?

8 Replies
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Like all drugs they can take up to three months to really work so be patient and if your concerned contact your rheumy.xxxx

Hidden
Hidden

Hi. I've been on it nearly 3 months. I also had extreme acid reflux and other side effects. I take four a day now and I have only just started to feel some mild improvement. This has been the slowest-acting drug I have ever tried.

It seemed to make no difference to me both when I started and stopped.

There are lots of people here on sulphasalazine successfully, but it does vary a lot. Unfortunately I'm sensitive to sulphonamides and came out in a beautiful classic rash after only the first day, so another choice out of the window.

I've been on it 10 years now, initially 4 per day then they up'd it to 6. I haven't had any side effects that I know about. Earlier this year my RA got markedly worse, mostly in my hands, and as I work with them it is a major problem to me. So I have now been put on Hydroxychlorquine as well. Been taking it a Month now with no improvement, has anyone had similar experience?

Hi

I was on sulfasalazine for ten years. 6 tabs a day. Worked well and after ten years stopped working.

Make sure you have coated version to min tummy problems.

Hi I only take 20 mg meth inj now had bad like flu quit often at first last one over a year ago had a heart attack 3 years ago said it could be the RA maybe get checked out Hope you get to feel better it takes time

Hi I got diagnosed about 7-8 years ago,

I started on sulfasalazine with 2 tablets daily ended up with 6 daily after 3 months . For me they were useless I’m now on methotrexate and Orencia injection and doing a little bit better . I had severe side affects from salfasalazine

I can’t take any medication with steroid due to my cluecoma, I also experienced

Uvicitis in one of me eyes due to ra .

Good luck with sulfasalazine give it time but you are on a very low dose , if you get a lot of side affects like bad anxiety or depression it Will eventually pass after 5-6 weeks but give it time .

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