Hi there .. I've read the general thread on this subject and of someone's unfortunate reactions with bruising/swellings to the Biosimilar. What I haven't managed to ascertain and my apologies if I've missed it, but I presume that if you have a Biosimilar infusion which you are allergic to that you have to wait until the minimum time has elapsed (six months is the usual minimum time until you can have a repeat Rituximab) until you can return to original Rituximab? As I plummet so quickly without medication and get inflammation very soon, this would be a nightmare for me and I would get more joint damage quickly too. This has happened when changing over meds in the recent past. Anyone been given any information on what hapoens if you have to change back? Thank you.