Advice please! Not allowed Methotrexate... - NRAS

NRAS

36,425 members45,074 posts

Advice please! Not allowed Methotrexate...

LizzieR profile image
4 Replies

Hi,

I have PSA. I am on Benepali and have been on mtx, but gradually reducing it from 25 to 5 mg. Each time, even with reductions, my blood count has gone so low that I've had to come off it. My rheumy nurse rang me to say that I'm going to have to come off mtx altogether. I have an appointment to see them next week now. I have a permanent damage in all my joints, but since coming off the mtx the throbbing, stabbing pain of the active disease ( I know you all know it!) I'm worried that without mtx the disease will just keep going... The rheumy told me this last time ie She hoped I could stay on mtx because she said that without it, the disease would ' find a way round' the Benepali. Any one been in the same situation? Obvs not asking for medical advice- just info!

Thank you,

Liz

Written by
LizzieR profile image
LizzieR
To view profiles and participate in discussions please or .
Read more about...
4 Replies
Sanbanan profile image
Sanbanan

Hi Lizzie.

I also have PsA and had to come off Methotrexate quite some time ago due to bad reactions.

I am now on my 4th Biologic after failing on various meds. I am currently taking Sulphasalazine with Cosentyx but still no huge improvement unfortunately.

It's always a concern as to what damage is going on when nothings working particularly well.

X

LizzieR profile image
LizzieR in reply to Sanbanan

Thank you. I hope you- we- find something soon x

nomoreheels profile image
nomoreheels

I'm sorry to hear you seem to missing MTX Lizzie, what you describe sounds like disease activity so it appears it was doing something. As I understand it MTX is used alongside anti-TNF's/biologics as it appears they work better with it's support, they seem to become more effective. That said for those who can't take MTX for whatever reason other DMARDs have been used so don't panic, I'm sure your nurse will be able to recommend where you go next. I know it probably feels an age away til you're seen but I wouldn't think much will happen erosion wise in a week. Do you have any NSAIDs prescribed? They may help a little with the inflammation & in turn pain.

Let us know how you get on next week, what's suggested.

LizzieR profile image
LizzieR

Thanks nomoreheels x

You may also like...

To increase Methotrexate or not advice please

Have little flares of various joint of my hands. They last 24-48 hours and since starting Mtx 15mg...

Methotrexate advice please!!!!!!

pains all through the night and today I feel like I have the flu!!!!!! Does anybody know if I can...

Fed up with Methotrexate...want to stop taking it completely. Some advice please?!

I'm experiencing more and more side effects of the mtx injections (tolerated 20mg weekly for about 5

Methotrexate drug combinations - advice please

I'm on mtx 15mgs weekly but haven't had any improvement in the last 4 weeks (18weeks in total)....

Starting Methotrexate. Any advice on when to have blood tests and take folic acid please?

folic acid and when to have the fortnightly blood tests. I'm planning to take MTX on Tuesday...