Humira Question

[Cjbrucks]

I have been taking Humira for a few months now. I noticed that it does seem to be helping a lot. However I can tell when it is getting close to shot day as I seem to hurt more in the couple days preceding my shot. Does anyone else notice this, or it is just because it is still building up in my system?

[Matilda7]

I've found the opposite. I've been able to space the injections out i.e. only take them every 4-6 weeks. But I have very low inflammatory markers...what are yours like?

[Cjbrucks in reply to Matilda7]

When I first started my sed rate was 87. Last test showed it at 34. I'm hoping by my next test it is in the normal range.

[Matilda7 in reply to Cjbrucks]

That probably makes the difference. Hopefully when your ESR and CRP are normal you will not have the painful days.

[Barrister]

I don't take Humira any more but when I was using it, I did find that I was in more pain for a couple of days before my injection. Clemmie

[Gigi71]

When I took Humira 8 years ago, it took about 3 months, before I noticed any benefit and by month 6, felt so much better. I had erosive RA and originally dx with lupus as well. My DMARD I was on was Azathoprine and NSAID was voltorol R together with oral steroids and had been for many years, these were clearly not working as so much joint damage. My inflammation markers were high, all this improved when I went on Humira. It's not usual to be offered anti-TNFs or biological meds so early on in their journey, with methotrexate and other DMARDs the first meds given. I changed to methotrexate in September this year and would say it was week 12 before I would say it was working. We are all different in how we react to drugs, so I would give it time to settle in. All the best. X

[Pands]

Hi, I have been on Humira for 9 years now and I go though periods where the couple of days before my next injection I am more stiff and creaky. So yes it definitely happens to me - just not all the time.

[Karen77]

That happened to me. It more than likely means it's not lasting long enough. My rheumy upped the frequency of shots to every 10 days.

[Cjbrucks]

Thank you everyone. It's nice to know I'm not alone on it. Last two days were very difficult but I took my shot last night and already feeling a little better this morning.