Sulfasalazine: Hi. Just been prescribed  Sulfasalazine... - NRAS

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Sulfasalazine

Megan2005 profile image
12 Replies

Hi. Just been prescribed  Sulfasalazine along with leflunomide which I have been taking for the past 3 years, in so much pain , just hope this works. Anyone out there know of any side affects. Thankyou. 

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Megan2005 profile image
Megan2005
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12 Replies
gwynedd profile image
gwynedd

Hi Megan, 

I've been on sulfasalazine for about 4 months, had a bit of a bad tummy for the first week or so but have been fine since. Except for bright orange pee! I hope it works for you and you get some relief from your pain. 

Megan2005 profile image
Megan2005

Thankyou for your reply. I'm feeling ver nauseous at the moment hope it goes soon.

Crusee profile image
Crusee

Hello,

Yep same with me,orange wee and also significant hair loss.

However I was also on mtx jabs at the same time so don't know if they reacted with one another or whether it was just the sulfasalazine.I was on 6 tabs a day and even when I was cut down to 3 per day it made no difference to the hair loss.

Hope you get on with them ok and that they work for you.

Crusee

XX

sylvi profile image
sylvi

I am on sulpha and i haven't had any side effects.xxxx

Hi I last take sulfasalazine 500mg tablets 4 a day, with no side effects at all, it's wonderful for me, I changed from mtx to sulfasalazine as couldn't tolerate mtx, and been totally fine. Apart from the yellow urine, but it isn't a problem and is safe to see this. Good luck, hope you tolerate.

Lady B 😊x

beckywebb04 profile image
beckywebb04

I had a horrendous sore throat, was in tears with it and felt like I'd swallowed razor blades then drank acid. Couldn't eat or swallow. Apparently that's rare though because I had to figure it was caused by the sulfasalazine myself

nomoreheels profile image
nomoreheels

I've also just this last week started sulfasalazine, just the one tablet this week & not had any side effects. It's been added to MTX due to disease activity in my feet. I always read the patient information leaflet when I start something new but tend not think about what I may or may not expect otherwise I think you just wait for them to happen. Just my coping mechanism I suppose. No really answering your question but I'm sure someone will be along who's been on it some time & pass on any side effects they've experienced.

moomie profile image
moomie

I ha e been on it for nearly 6 years, initially had a brilliant response. I was able to come off long term steroids.

Now take 6 a day plus hydroxy and mtx.

Only side effect I get is Sun sensitivity. I am fair skinned though. Just remember to apply high 

moomie profile image
moomie

P.s tablet playing up and cut out and posted.

Apply a high factor cream even in winter when the Sun is out.

Hope it works well for you. Good luck Moomie

beeckey profile image
beeckey

just made me feel ill no appetite hope you do better on it

wannabhealthy profile image
wannabhealthy

Been taking 6 tabs SULPHA per day for last 16 months + MTX + HYDROXY.  Few teething probs for first 4 weeks but fine now.  Good Luck!

Vixen2 profile image
Vixen2

i know this post’s 7yrs old!!! But i’ve had RA for 31yrs. (Since i was 21). I was first put on Sulphasalazine. (About 4 a day. About 3 a day of Indocide, steroids & co codymol & co dydramol). I felt very ill on them. Felt sick constantly. Had to eat a lot of mints to ease the sickness. Then 1 day i couldn’t recognise my brother in law. I was totally confused. Couldn’t read or write. I was a zombie. Felt so ill. My consultant lowered the doses the next day. I was fine. Then the nausea just seemed to vanish. It just shows you how strong these drugs are.

Now i have an infusion of Infliximab every 6 weeks. I’ve been on this drug for 20yrs. Thank God for the NHS. I know this post was 7yrs ago. So i’m not expecting a reply!

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