Omoperazole: Does anyone take Omoperazole while taking... - NRAS

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Omoperazole

nellysgran profile image
23 Replies

Does anyone take Omoperazole while taking MXT ?

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nellysgran profile image
nellysgran
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23 Replies
Luthien66 profile image
Luthien66

I've been taking Omeperazole since starting RA meds and yes took them when I was on MTX, although have come off MTX at least a couple I years ago. I'm still taking Omeperazole.

kizzy12 profile image
kizzy12

hi..yes i do..wouldnt be without them...have been for 18mnth now with no probs

PB1950 profile image
PB1950

Hi Nellysgran been on Omoperazole since 2006, started one a day now because of the increase in Declofenic, taking it 3 times a day also still on the Metho. 22.5mg.

in reply to PB1950

Omaprazole can contraindicate with MTX because it's a proton pump inhibitor - it says so on the MTX info sheet I think - but if this happens to you then you could switch to another stomach protector like Zantac which doesn't have this effect. RArebird x

Scarlet-Poppy profile image
Scarlet-Poppy

Hi there. I also take it with 22.5 mg of MTX and haven't had any problems. Before I took it I used to get horrible heartburn but all fine now! I'm sure the consultants must know if it's an ok combination?!

Rarah profile image
Rarah

Yes I do

julie_warwick profile image
julie_warwick

yes I take it to. it's to protect your stomach from all the other drugs , it is contra indicated with mtx as it can inhibit the excretion of mtx but as far as I understand at the doses taken for RA it is not a problem , more of an issue for people taking it at chemotherapy doses . but check with doc as I may be wrong x

Scottishlad profile image
Scottishlad in reply to julie_warwick

I queried this when I was back to get a repeat prescription after trying Omperozole . I understand the problem is with the high doses of methotrexate used in chemotherapy. The dose for RA is a fraction of the chemotherapy one.

Rosie_rabbit profile image
Rosie_rabbit

Yes I take it too. First had it prescribed when I was taking naproxen. I stopped it a while after I stopped taking the naproxen and was ok for a bit. In the last few months though I've been getting horrible heartburn and reflux, the only thing I'm taking is 20mg of mtx (and folic acid) so it must be the mtx causing it. Now take the omeprasole again and I'm fine. Rx

Linda-D profile image
Linda-D

I've been on Omoperazole, MTX and other medications for many years. I've had no problems.

chrispe profile image
chrispe

I take it because of the mobic 15mgs i take for pain. Chris x

drugs.com/drug_interactions...

I always use the drug interactions checker on Drugs.com and, although I have been prescribed Omeprazole, I don't actually take it and it is worth talking to your doctor about these 2 drugs

I take MTX amongst other things

nellysgran profile image
nellysgran

Thank you all for your replies, I was on Lansoperazole but after visiting my Gp last week she changed to Omoperazole then I read on the paper with the meds that you shouldn't take with MXT, but now I see that many of you are taking both, thanks again, now not sure what the difference is between the two ??

Hope you are all pain free, Wendy x

Speedwaygran profile image
Speedwaygran

Yes I do. As I am also on meloxicam and HQ it was recommended I stay on it.

RUBELS profile image
RUBELS

Hi Nellysgran I take omeprazole and mtx. Touch wood (head), with no problems

KylaC profile image
KylaC

I am on MTX and take it too as I am on high dosage slow release Breufen so I helps protect my stomach

zannie profile image
zannie

I take MTX and Omeperazole, and I feel fine. My nurse told me that the Omeperazole is to help digestion . It certainly helps me. I hope you have the same advantage. XX

Riedenise profile image
Riedenise

HI Ive been on Omeprazole since Aug 2012, I was put on it when I was put on Naproxen. I got diagnosed with RA Jan last year & take it along with MTX,Hydroxy,Sulpha, folic acid also. Don't seem to be having any problems with it, Gp seems happy as been on it nearly 18 months.

Psychic profile image
Psychic

I take Omeprosole and MTX, have not found any problems.

Paulable profile image
Paulable

Hi, I take Omoperazole with my Ibruprifen retard tablets. I have metoject50 injection weekly. Why do you ask?

wendy1934 profile image
wendy1934

I was taking omeprazole from 2007 till last summer when I started getting very bad stomach upset that went on for quite a few weeks---I stopped taking omeprazole & problems stopped. I have been on rituximab since 2010 plus hydroxychloroquine tabs. So for pain killers I take paracetamol & co-codamol---not at the same time!

Hi! I take that and sucralfate 1 GM pill 2 times a day to protect my stomach. So I'm goo with that!!!

Titchyj profile image
Titchyj

Hi nellysgran, I have been on omeprazol 20mg twice a day for many years, due to GERD, I have recently been prescribed MTX, but not yet taken them due to a viral infection, but the Rheumy nurse told me to leave 4 hours between the two meds., because of the interactions.

Hope this is of help.

Jan

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