Hi all. I am in my 10th week on mtx and an due to have my second week of injection on friday. Side effects were so bad with tablet form that i started last week on injection. This is done at rheumy clinic every friday for next 8 weeks until stabilised i have 15mg and then will be able to do them myself via gp. Problem i have is although RA has improved the side effects are driving me mad. I now hav 3 mouth ulcers one of them in side of my mouth which will not go and is keeping me awake at night. I just dont know whether it is worth it any more as so fed up with feeling lousy with mtx. Still feeling really tired and aching wrists so dont know whether to stop the meds and just take my chances with the RA. My feet and knees are much improved but still hav to watch what i do as feel as tho it isgoing to flare at any moment. Cant see light at end of tunnel at moment as unwell with the RA and unwell with mtx. Only fully diagnosed in july and already had plaquenil which was awful. On folic acid 3 times a week and arcoxia. So fed up at moment. Sorry for going on just dont know when i will finally accept this.