Fexofenadrine warning

[skodaguy]

Recently saw Claire because itching has been a real torment lately. She recommended I try fexofenadrine so I looked it up . Was surprised to find that apple, grapefruit and orange juice can reduce its effectivness by up to 40% if taken either 2 hours before or after taking the drug. This is a recent finding and is not on the drug information leaflet. Looks like it was only published mid August. Just google fexofenadrine and orange juice if you want to read more.

[Wyebird]

Gosh a mega important piece of information. I wonder if it’s the vitamin c that causes the interference. At the moment I’m trying to take extra Vit c to help absorb my iron and increase my haemoglobin level

[skodaguy in reply to Wyebird]

Something in orange/fruit juice interferes with a receptor in the gut which prevents drug absorbtion

[Loubprv Volunteer]

Even worse, Fexofenadine can cause the most frightful tinnitus.

I was prescribed this for a completely different reason ( I have histamine intolerance caused by an antibiotic called Nitrofurantoin which caused me to have tinnitus in my right ear)

I tried Fexofenadine only once and it made this ghastly tinnitus much much worse.

Read the Fexofenadine side effects bumph in the packet and it said “ can cause ringing ears” - they didn’t tell me that either!

Approach EVERY drug with great caution would be my advice.

Best wishes,

Louise.

[yarrowleaf]

Hi!! Anti-oxidants interfere with your sort of antihistamin. In my opinion Cetirizin and Loratadin is more cooperative !!! I have citrus fruit allergy and ET and have been taking these two antihistamins for more than 30 years without complications. I change every third month so my mast cells won't start "complaining" 😐

Ok. I am not you, but give it a chance.

Have a great Sunday.

Yarrowleaf

[Rachelthepotter]

Have you tried the certirazine + ranitidine combination that I’ve heard Rueben Mesa recommend ? ( and I see its on the pvreporter website that was posted here earlier today) Zyrtec plus Zantac in American branded terms.

I’v only had a very short spell of itching, and I do sympathise.

Rachel

[Pablo1]

Hi i had been on Hydrea x 3 for around 13 years. Towards the end i had i lot of itching & red skin. Someone suggested beetroot juice. I thought it wouldnt hurt, had it twice a day for 2 days. Day 3 everything cleared up. Just had red urine as a side effect for a couple of days. This juice is full of iron, vitamins & minerals.

I believe the drugs we are put on destroy the lining in our gut. So we are nutrient deficient. Anyway worked for me... make sure u drink heaps of water as well.

Good luck

Monique

[Hearingu]

I have the same problem . Have been on fexofenadine for over a year and started itching recently . Looked at leaflet and can be side affect . However did help originally so worth a try. Seeing consultant tomorrow for options . On Pegasus for PV Been great ! Just the itching 🤨Perhaps it’s the apples!

Good luck and remember we are all different .