Vitamin D Deficiency in Patients with Systemic Lupus Erythematosus

Vitamin D Deficiency in Patients with Systemic Lupus Erythematosus

Vitamin D deficiency is frequent in patients with SLE. Patients with SLE have a higher risk of developing 25(OH)D deficiency in the presence of low serum C3 and C4 levels, and high anti-dsDNA levels.

Full text of paper at link here

7 Replies

  • I was diagnosed with sle 2 years ago and was told im vitamin D deficient, my GP prescribes daily supplements of vitamin D apparantly most lupus patients are routinely tested for this as its goes with the illness. Im also protein S deficient, thanks for some informative reading.

  • Hi Sophieh, what's protein S?

  • Hi roobarb, protein S deficiency is basically an abnormality of blood clotting. People who are deficient are at a higher risk of blood clots so i take aspirin everyday! Around 1 in 20,000 people are diagnosed with it, but im not sure if lupus patients are more at risk? I seem to have absolutely every possible disorder lupus related or not lol!

  • Thanks Sophie, I'm learning all the time. I hope to stay as well as possible. X

  • Thanks Ted, for interesting link. Think I'd better up my dosage then. :)

  • I've never been tested for vit D deficiency despite being diagnosed with SLE 5 years ago, & being extremely sun sensitive. So I've started to use an over the counter vit D oral spray, & informed my rheumy of course.

  • I have Lupus, Sjogrens Syndrome, Fibro, RA, APS, Osteoporosis, Osteoarthritis, 2 major strokes, 5 t.i.a. s, angina, MVR, Temple Arteritis, Vasculitis, Raynauds Syndrome, RLS, degenerative disc disease, & have had a radical mastectomy of my left breast due to cancer! Had radiotherapy but couldn't have chemo because of my poor health!! Now I've been dx with Hyperparathyroidsm due to vitamin D deficiency!! I am on a strong vitamin D tablet! Was told by the specialost I saw (a different one not for Lupus) that mine was bad & usually they would operate but because I can't have a general anaesthetic I couldn't have it done!! I am just being monitored now! I have chronic anaemia aswell as a lot of other things! Have 2 appointments next wk, rhuemy for Sjogrens (I go to St. Thomas for Lupus) & the next day I have to see a gynae specialist as my bowels have dropped aswell as my bladder! The wk after I have my mammograme. I seem to be for ever at the hospital or Dr's. I'm in a wheelchair & have had a couple of falls transfering in the bathroom, but 2 wks ago was washing my hands when I fell very awkwardly & my back slammed in to the toilet & I screamed for my husband who came running & the next day went to the Dr's who told me to go to x - ray, had it done & was told to call my Dr later in the afternoon. Phoned her & was told I had a crushed vertebrae of the L 2 at the base of my spine which apparently this vertebrae affects the hip too, & have been in agony with it! Waiting to hear from Kings hospital where my Dr is sending for an opinion about my back! I feel like I'm going crazy! Sorry to have gone on so much I really am!

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