Hydroxychloroquin increase: Hi everyone, just a... - LUPUS UK

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Hydroxychloroquin increase

Biddy47 profile image
16 Replies

Hi everyone, just a quick question. I have a new rheumatologist and he has increased my Hydroxychloroquin from 200mg a day to 200mg one day and 400 on alternate days. On the day I take the 400mg should I take both tablets at breakfast or take 1 at breakfast and 1 at dinner? Thanks.

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Biddy47 profile image
Biddy47
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16 Replies
maggielee profile image
maggielee

Hi I take them one breakfast & one dinner after eating....ml

Boudica1 profile image
Boudica1

Hi, I'm on 400 a day and take one in the morning and one in the evening as that is what the doctor said.

GlasgowHen profile image
GlasgowHen

I’m on the same regime as you. I take both in the morning. I have to take it with food and because of gastro issues I eat very little in the evening. Seems to work.

Hope it works well for you. I found my energy levels in particular really benefitted from the increase

GlasgowHen profile image
GlasgowHen

It’s quite common to be prescribed this dependent on body weight. I’m a light weight, 400mg every day would be too much so an accumulative dose of 300mg is more suitable.

Hydroxychloroquine is a long term medication so prescribing an accumulative dose is fine.

Biddy47 profile image
Biddy47 in reply to GlasgowHen

Thanks as I said to Pippa it's because of my weight, I'm light too.

GlasgowHen profile image
GlasgowHen in reply to Biddy47

Hi biddy, my reply above was to pippa as it seems she was concerned and it’s quite a common practice.

Hope the increase works well for you, it certainly made a difference to me

Jmcb123 profile image
Jmcb123

This is same dosage regimen as me, I split the 400mg, one in morning, one in evening and take the 200mg day tablet in evening. No reason to be concerned about dose, I’m a pharmacist and dose is weight/symptom dependent. X

Biddy47 profile image
Biddy47 in reply to Jmcb123

Precisely what Con. says. Thanks

freemare profile image
freemare

Hi

I’m in the US. I do not have a Lupus dx but I have a lot of the symptoms so my Rheumatologist treats me accordingly.

I have Undifferentiated Connective Tissue Disease and Severe Fibromyalgia and a dozen other things. I’ve been on 200mg 2x a day for three-four years and I take one in the morning and one in the evening.

If you take anything for your stomach, make sure you take it a few hours apart from the Hydroxychloroquine (I have/had Barrett’s Disease and GERD, Acid Reflux and a hiatal Hernia; so I’m on Pantoprozole 2x day also which I am lucky if I take one a day because I’ve taken my meds and then forget to take it later!).

~Mare

Sara_A profile image
Sara_A

I used to take 400mg daily, 200mg am and 200mg PM as found it was better on my tummy that way.

Was on this a out 10 yrs. Had to stop recently as possible eye issues.

Biddy47 profile image
Biddy47

He is a consultant rheumatologist. Apparently it is according to my weight. What makes you worried Pippa?

nanleighh profile image
nanleighh in reply to Biddy47

Don’t worry, that is a normal dose, and a life saving medication for many of us. Hugs, Nan

Hamptons profile image
Hamptons

I take 400 and 600 to stop me taking giant amounts. Reduced from 800 daily.

Gmagolf profile image
Gmagolf

I take one after breakfast and one after dinner

amwas profile image
amwas

Hi Pippa. Try not to worry. I was on 400 mg daily two tablets of 200 taken together after food. I was on these for a decade and they did help over time. Now the recommendation is for 5 years treatment duration so I was suddenly stopped 3 years ago. To no ill effect for me, anyway.

Lupus is a difficult disease but once the appropriate treatment on an individual basis is established it helps. I had azathioprine for 5 months each year for two years but had side effects to my liver so I stopped this med. I also took prednisone on and off for 8 years.

I am a psychologist so was able to access a good rheumatologist eventually after a few

Experiences of feeling like an experiment!

Treatment is much better 12 years on from my diagnosis.

Paul_Howard profile image
Paul_HowardPartnerLUPUS UK

Hi Hidden ,

It is not uncommon for hydroxychloroquine to be prescribed in this manner. As it is prescribed based on ideal body weight, a proportion of people will not match a 200mg or 400mg daily dose. This is an equivalent way of prescribing a 300mg dose. It would be easier if the tablets were available in doses of a size different to 200mg.

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