Gabapetin and drug induced lupus?: Hi! Does anyone... - LUPUS UK

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Gabapetin and drug induced lupus?

dgleds profile image
15 Replies

Hi!

Does anyone know how long its takes for Gabapetin to totally leave your body...without a trace? Im crummy at the calculations they do ....

Also if you know or not, if its one of the anti sezuire drugs that can cause drug induced lupus? Might be spelled gabapentin...neurotin I think its other name...

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dgleds
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15 Replies
misty14 profile image
misty14

Hi Dgleds

I can answer part of your interesting questions. I take Gabapentin and it is an anti seizure medication but not one of the ones that can cause drug- induced Lupus!. I've taken it for years now and been fine. I don't know how long it takes to leave the body, i do reduce the dose from time to time and feel better quickly so it could be fairly fast!

Hope I've been helpful?. Are you changing drugs?.X

dgleds profile image
dgleds in reply to misty14

SUPER HELPFUL!!!! you just answered the other part of my question misty14...THANK YOU :) I was diagnosed with lupus last year (mild), and had been on Gabapentin prior for 4 years for my back disc things....I took low dose, but had just gone off it about one month before he took blood ANA test for lupus...I never told him Id been on it, cause never gave it a thought, and didn't know about drug induced lupus...I found out Gabapentin doesn't stay in your body very long when you go off it...I think every six hours its half as much as your initial dose....Might have 1 percent in your blood a week later, but not likely...Of course its in your blood if your taking it every 8 hours etc....

I thought cause its an anti sezuire drug, it mighta been one of the drug induced lupie ones...Ratssss!!!! Oh well, still trying to accept my diagnoses...Im one of those look at every angle types...Thanks again....

misty14 profile image
misty14 in reply to dgleds

Hi Dgleds

Glad I've helped you and I'm pleased that Gabapentin doesn't stay in our bodies long!. Good luck for your ANA results. Your right to want to know things, we have to cope with the outcome of what we put in our bodies, the docs don't!.X

mar777y profile image
mar777y in reply to dgleds

This person gave their person experience, and here is mine. I did turn up with a positive ANA after taking Gabapentin for nerve related injury pain, and the followup DaDna or something like that was negative last time, they are repeating this. Not sure if this is a false postiive because of the Gabapentin, or if I had the lupus all along, even before the drug, or if I actually have lupus right now, and it was caused by gabapentin. My symptoms didn't get worse while on this medication, I have gained some weight over the years, hard to lose disabled but I am still going to try hard to lose the excess weight now, harder than I have tried in the past. I think that could help me a great deal to some degree, because of course excess weight has it's own challenges which I could do without. Best of luck. I wouldn't take this person's personal experience as medical information, just that they didn't get lupus while on this drug. I do think it could be related as some anti-seizure medications have been known to cause a positive lupus test. Waiting for what the doctor finds with a new follow up test (new doctor too). I have just thought is was a false-positive, but he will tell me more. There are tests that should be able to tell you if it is caused by a drug. walrus.com/questions/what-c....

retiredwindowshopper profile image
retiredwindowshopper in reply to misty14

I can't say that much about the lupus part, but my advice to anyone taking this drug is to go to your side effects of this drug and pay close attention to it. This says not all people are effected by this drug, but that does not mean that you are not from colds, runny noses, to staying awake and not getting enough sleep. This is just a small sample a very small sample of what it can do even from hair loss to breast enlargement so read up on it. To me this is not a good drug for no one. It sounds like a drug that needs to be taken off the books with all the side effects and I have not talked to one individual personally who has taken it that is still taking it so beware and read. I am not going to tell you not to take it, but I will tell you to read these real closely and read all drug informationon it's side effects. Who is to say that you are not just having one side effect or when one if not more could occur with this medicine. Doctors make a lot of money on bad drugs and good drugs.

mar777y profile image
mar777y in reply to retiredwindowshopper

I have taken it for a long time. The list of potential side effects is generally anything that people reported having during trials that may or may not be related to this medication, which is why they are listed as "potential," in part. I have taken it for along time for nerve pain, and it was able to reduce the pain to some degree which made it worth taking, along with using other things to help, but which did not do enough to keep me functional. I have however come up with a positive ANA test for lupus, but the follow-up test was negative for something like DaDna, not sure if that is the correct name of the test though. This might be what indicates if the drug is causing it as some anti-seizure medications have been known to cause a positive ANA, however I am also looking to see if it is caused by this drug, and whether the test will be negative if off of the drug. I don't seem to have any additional symptoms though, which make me think it is Lupus, unless it was lupus to begin with, but initiated immediately following a car accident and worsened with something further a year later.

dgleds profile image
dgleds

This doc was so fast to diagnose me...That I have to dig here and there to make sure...He called lupus on just ANA test and inflammation...all other tests were negative. But I know others here have had that similar experience too...

I so relate to this as I was diagnosed with RA three years ago but my problens have mostly related to drug intolerance's ever since. I find it impossible to accept I have RA a lot of the time.

Now on Gaberpentin and struggling with awful dizziness so can't drive or function properly and also a crushing sensation I can't quite describe with words - like doom and exhaustion rolled into one!

I've been told the shelf life is 6-7 hours - not like DMARDs that hang around. I'm giving it another ten days as my GP asked me to but so far not good. I don't think it would induce Lupus though. Some of the Biologic drugs can do this I know.

dgleds profile image
dgleds

I just read that Macrobid can cause it..thats an antibiotic..geesh!

linda65 profile image
linda65 in reply to dgleds

Is ciprofloxacin in that group?

in reply to dgleds

If it's drug induced Lupus I believe it goes away once the drug is stopped? Is this why you are hoping that Gaberpentin caused your Lupus? - sorry I'm being a bit slow on the uptake - blame the Gab!

dgleds profile image
dgleds in reply to

WEll...I was just thinking mayyyyyyyyybeeee the Gab, but looks like it couldn't be. But the timing with that drug and my visit was close...

My ANA was 320 and fine speckle and homogenous..

Drug induced lupus is homogenous lookin I think...(I read way too much)...

in reply to dgleds

I read way too much too but only about things that show up in my bloods. My ANA is negative so I tend to read about sero negative autoimmunity - which perhaps isn't as rare as the experts say it is.

Someone said the other day on the RA HU that Levothyroxine can cause RA and that freaked me out a bit because I've been on it for 12 years or more now. Reading stuff on Thyroid UK HU often makes me wonder as I had years of severe hairloss and rhinitis but I can't recall now whether it was before starting the Levothyroxine - think it was though. Then I wondered if all my peripheral neuropathy and dry eyes was a response to Amitriptyline recently too. I think it's hard when we take strong drugs for a disease that we don't altogether accept that we have?

dgleds profile image
dgleds in reply to

im on levo too...my hair is really thin now...but I saw a pic of me last night from 2003, and my hair was pretty thick. I started on levo in aprox. 1998....I think the thin came real bad about menopause time..2009ish, then lupus must have been in there about that time too...and good ol buckets of stress...I know I heard about thyroid and a type of arthritis, but also a menopausal arthritis...Its friggin hormones, I tell ya! PS/ My Gran had RA really bad...I never met her, but my Dad said she had it bad...

dgleds profile image
dgleds

Linda65:

Just punch in to Google, "does ciprofloxacin cause drug induced lupus"...I was doing that for Gabapentin but not much came up, which made me think nope...If your drug seems to be in lots of articles on google, then a better chance of yes...

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