Hi ive been diagnosed with depression on and off since I was 14 years old I'm 35 on Wednesday. I've been on anti depressantson and off over they years around 18 months ago gp put me on sertraline started does of 100mg now I'm on 150mg maximum does. I still feel like I'm battling wit everythingsimple things washing myself is so much effort. Doing the house work is hard. I'm fed up and miserable ive had enough of everything.