Hi, 25 year old female. I'm new here and Currently suffering with major depression and self-harm. I'm currently taking 100mg sertraline. I have an appointment to review this with my G.P. tomorrow afternoon. I have been on this for a few weeks now and I am feeling little to no benefit from it at all. I lack energy, have trouble sleeping, repetitive nightmares, major anxiety issues, panic attacks and general low mood. I have little to no support from family members at all and only one very close friend who is willing to help, but I don't want to burden her too much. Do you think I may need to consider changing my medication?