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1998 study found grape juice reduced level of blood stickiness better than aspirin.

Tranquility1 profile image
12 Replies

"A 1998 study found that grape juice can reduce the level of platelet aggregation _ the ``stickiness'' of blood _ better than aspirin . . . as long as it's purple grape juice. Results of the study were presented recently at the American College of Cardiology's 47th scientific session.

The study involved 10 subjects who drank a cup to a cup and a half of fruit juice _ orange, grapefruit or grape _ per hundred pounds of body weight daily for seven to 10 days, then drank no juice for a week, then switched to another of the juices until all had been tried. Orange and grapefruit juice had no effect; with grape juice eight subjects showed the lower levels of blood clotting."

articles.latimes.com/1998/a...

I haven't found any follow-up studies. Pharmaceutical companies cannot make money off telling people to drink 2 cups of 100% purple grape juice a day.

I tried researching if there were any studies against drinking grape juice while on warfarin. I couldn't find any. What I kept finding was the warning not to drink cranberry juice while taking warfarin. For those of you on warfarin, before adding grape juice, you may want to check with your doctor. In addition, if you do add grape juice, do it slowly and keep an eye on your INR.

I have always loved 100% grape juice. I feel like it gives me energy. Now I know why. :-)

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MaryF profile image
MaryFAdministrator

I hope it translates into a study on wine! MaryF

overnighthearingloss profile image
overnighthearingloss in reply to MaryF

K2 which apparently is a blood thinner is found in fermented foods. Just saying... .

Please remember to act responsibly :-)

MaryF profile image
MaryFAdministrator in reply to overnighthearingloss

Yes, on another note, there is a product around called fruitflow which is supposed to help with certain conditions, and presumably harnesses the type of affect which comes from probably eating the right fruit! MaryF

overnighthearingloss profile image
overnighthearingloss in reply to MaryF

OMG what a name

It sounds like a bowel clearance product

MaryF profile image
MaryFAdministrator in reply to overnighthearingloss

Some people do take it to help reduce platelet clumping! I think if was for a different effect perhaps a re branding... 'Maximum Prune' etc. MaryF

Tranquility1 profile image
Tranquility1 in reply to overnighthearingloss

(edited for link)

Be careful of K2, the more recent studies show that it thickens blood. There was a study on Vitamin K2 and it's impact on INR in those taking oral anticoagulants. In this study, they found that "A daily intake of 45 μg of MK-7 (Vitamin K2) significantly decreased the group mean values of both the INR and ucFII by ~ 40%. Daily intakes of 10 and 20 μg of MK-7 were independently judged by two hematologists to cause a clinically relevant lowering of the INR in at least 40% and 60% of subjects, respectively, and to significantly increase ETP by ~ 20% and ~ 30%, respectively. Circulating ucOC and dp-ucMGP were not affected by MK-7 intake. Conclusions: MK-7 supplementation at doses as low as 10 μg (lower than the usual retail dose of 45 μg) significantly influenced anticoagulation sensitivity in some individuals. Hence, the use of MK-7 supplements needs to be avoided in patients receiving VKA therapy."

onlinelibrary.wiley.com/doi...

In the above study, the anticoagulant being used was "Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is marketed under the brand names Sintrom and Sinthrome."

Lure2 profile image
Lure2 in reply to MaryF

Hi mary,

I agree on the wine!

Best to you from Kerstin

Manofmendip profile image
Manofmendip in reply to MaryF

I agree Mary.

Dave

Tranquility1 profile image
Tranquility1 in reply to MaryF

While there are many studies on the positive impact of a glass of wine a day, it doesn't look like drinking wine will decrease platelet stickiness. Here is a study from 2004.

"Twenty-four healthy subjects participated in this randomized crossover study. Each subject drank either a half bottle (300–350 ml, approximately two glasses) of red or white wine during dinner on two separate occasions. Blood samples were taken on the morning of the scheduled wine consumption and at the same time on the morning after the wine consumption. Platelet counts, and thromboelastogram (TEG) were performed and platelet function was assessed by adenosine diphosphate (ADP) and collagen induced platelet aggregation tests.

There were no significant changes in platelet number, platelet function and TEG values the morning after wine consumption, and there were no significant differences in platelet number, platelet function and TEG values between red and white wine. This study indicates that an intake of red or white wine during dinner does not affect platelet number, platelet function, or viscoelastic properties of blood the next morning. A half bottle of red or white wine intake prior to a next day's elective surgery has no significant risk of suppression of coagulation function."

informahealthcare.com/doi/a...

MaryF profile image
MaryFAdministrator in reply to Tranquility1

I was being tongue in cheek, I drink a glass or pure purple grape juice daily, every morning! MaryF

Lure2 profile image
Lure2

I take a wellknown bloodpressure-drug here in Stockholm since at least 10 years. Grapefruit is forbidden when taking this drug!

So grapefruit is the only fruit and also the juice I avoid.

Kerstin

Reading a book on liver flushing by Andreas Morritz at the moment.

Suggestions that gallstones in the liver that are not usually picked up on scans as they often are not mineral in origin may congest the liver and indirectly prevent normal liver functions which can indirectly lead to auto immune type conditions and blood stickiness.

The jury is out with me at the moment but will read it all first

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