Hi all I haven't been on here for a while but thought I'd share my problems. I can't remember the last time I felt well. I have pains in joints and muscles am always tired, don't sleep well and my INR is all over the place. Am a bit confused by this really. My range is 2.5 - 3.5 but for the last 3 tests it has been 2.3. The hospital have an INR nurse to determine dosage and although this is below my range has kept me on the same dose of Warfarin. I phoned them and said this was not acceptable because if my INR is below 3 I get cluster migraines. The male nurse I spoke to said they obviously weren't checking my range and put my dose up. If this is the case they shouldn't be doing that job in my opinion as checking the patients range is quite important I think. The doctors don't set a range for the fun of it . Still I have an appointment at St Thomas's in October so hope to get some joy from them. I want to discuss changing from Warfarin onto another anticoagulant as I wonder if all my health problems are a reaction to long term use of it ( approx. 25 years). Does anyone have any thoughts on this?