'Calcium deficiency is a common nutritional concern, but how many folks consider the vital importance of magnesium in human health and disease?
New research published in the journal BMC Bioinformatics indicates that magnesium's role in human health and disease is far more significant and complicated than previously imagined.
While it is well known that all living things require magnesium, and that it is found in over 300 enzymes in the human body, including those enzymes utilizing or synthesizing ATP (the molecular unit of currency for energy transfer), the new studied titled, "3,751 magnesium binding sites have been detected on human proteins," indicates that a deficiency of magnesium may profoundly affect a far wider range of biological structures than previously understood.
The proteome, or entire set of proteins expressed by the human genome, contains well over 100,000 distinct protein structures, despite the fact that there are believed to be only 20,300 protein-coding genes in the human genome.
The discovery of the "magneseome," as its being called, adds additional complexity to the picture, indicating that the presence or absence of adequate levels of this basic mineral may epigenetically alter the expression and behavior of the proteins in our body, thereby altering the course of both health and disease.
Indeed, modern medicine and nutrition fixates primarily on calcium deficiency (due, in part, to the WHO's highly unscientific definition of osteoporosis), even in the face of accumulating peer-reviewed research indicating that excess calcium consumption can greatly increase cardiac morbidity and mortality.'