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Dutasteride increases PSA Doubling Time after PSA Recurrence
These two Kaplan-Meier plots compare Dutasteride (0.5 mg/day) to Placebo in a randomized, double-blind trial from 2012 of 187 men who have progressed to
PSA Failure.
In the upper plot, Dutasteride increases the
Doubling Time
from, for example, 9 months to 18 months (factor of 2X). In
These two Kaplan-Meier plots compare Dutasteride (0.5 mg/day) to Placebo in a randomized, double-blind trial from 2012 of 187 men who have progressed to
PSA Failure.
In the upper plot, Dutasteride increases the
Doubling Time
from, for example, 9 months to 18 months (factor of 2X). In
janebob99
in
Advanced Prostate Cancer
2 days ago
Dragging a millstone up a mountain. RLS blind spot, patient’s apparently don’t know best.
Hello friends, it’s a while since my last post but was waiting until I had some good news to share with you all but as the title of the post indicates the opposite. I have a wonderful Consultant Dr Jose Thomas who specialises in sleep disorders and RLS, the downside is he is based in Wales uk and I
Hello friends, it’s a while since my last post but was waiting until I had some good news to share with you all but as the title of the post indicates the opposite. I have a wonderful Consultant Dr Jose Thomas who specialises in sleep disorders and RLS, the downside is he is based in Wales uk and I
HipHop1972
in
Restless Legs Syndrome
4 days ago
Orgovyx and Zytiga with adding Prozac, good or bad?
Poollover wants to know if adding Prozac would cause a problem with androgen deprivation drugs?
Poollover wants to know if adding Prozac would cause a problem with androgen deprivation drugs?
Poollover
in
Advanced Prostate Cancer
14 days ago
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selenium supplements
what are the best type? My husband has just purchased some which seem to say both sodium selenite and selenite, 100 ug,, not sure if is the correct compound. The instructions are in small Turkish language/ print n fortunately. Any comments? had not noticed autocorrect must have worked paper stuck on
what are the best type? My husband has just purchased some which seem to say both sodium selenite and selenite, 100 ug,, not sure if is the correct compound. The instructions are in small Turkish language/ print n fortunately. Any comments? had not noticed autocorrect must have worked paper stuck on
Judithdalston
in
Thyroid UK
15 days ago
supplements help?
hi there, does anyone with hypothyroidism take supplements that contain kelp? I’ve had conflicting advice on its use/benefits for hypothyroid sufferers. I’m considering starting Thyroid Support with L-tyrosine and Kelp from Cytoplan, but don’t want it to have an adverse effect. Thanks
hi there, does anyone with hypothyroidism take supplements that contain kelp? I’ve had conflicting advice on its use/benefits for hypothyroid sufferers. I’m considering starting Thyroid Support with L-tyrosine and Kelp from Cytoplan, but don’t want it to have an adverse effect. Thanks
Aquariu5
in
Thyroid UK
18 days ago
Switching From Adalimumab to Benepali
After a few years with Adalimumab with increasing skin psoriasis to the hands and back of head one my rheumy has advised Benepali ...not because I love Italian food but it was havoc on my skin. I ask has anyone had a transition with these two biologics with any symptoms?
After a few years with Adalimumab with increasing skin psoriasis to the hands and back of head one my rheumy has advised Benepali ...not because I love Italian food but it was havoc on my skin. I ask has anyone had a transition with these two biologics with any symptoms?
Frankiefocus
in
NRAS
21 days ago
Things, regimens,etc that are probably RLS worthless.
THINGS THAT DO NOT WORK FOR RLS All of us with RLS/PLMD have slightly different symptoms. We have tried various 'remedies' to try to relieve our RLS symptoms. We have read articles, some interesting, some ridiculous (bar of soap) that make amazing promises. And there is an entire array of things to
THINGS THAT DO NOT WORK FOR RLS All of us with RLS/PLMD have slightly different symptoms. We have tried various 'remedies' to try to relieve our RLS symptoms. We have read articles, some interesting, some ridiculous (bar of soap) that make amazing promises. And there is an entire array of things to
fritz34
in
Restless Legs Syndrome
1 month ago
biotin supplements
Hi all! My hair is thinning again , I think due to hrt I’ve changed and I remembered seeing many of you are taking biotin for hair loss. Can anyone advise me as to what dosage and make has worked for you? Looking on Amazon , there’s a wide array of strengths and prices …. It’s very confusing! Thank you
Hi all! My hair is thinning again , I think due to hrt I’ve changed and I remembered seeing many of you are taking biotin for hair loss. Can anyone advise me as to what dosage and make has worked for you? Looking on Amazon , there’s a wide array of strengths and prices …. It’s very confusing! Thank you
LinaM
in
NRAS
1 month ago
lupus - itchy scalp and hair lost
Hi everyone, not sure if anyone has experienced itchy scalp like it. Even apply the Novasone ointment, still very itchy and and it also has something like plaque…. Also, I experience lots of hair loss and hasn’t recovered. Anyone can share some tips that would be great. thank you
Hi everyone, not sure if anyone has experienced itchy scalp like it. Even apply the Novasone ointment, still very itchy and and it also has something like plaque…. Also, I experience lots of hair loss and hasn’t recovered. Anyone can share some tips that would be great. thank you
Kim_21
in
LUPUS UK
1 month ago
Cold cap advice?
Im a very lucky gal whose cancer was caught early (by accident) at stage 1c. I've had surgery and about to start chemo tomorrow. Carbopentin only. They booked me a cold cap as I was originally going to have Carbo + Taxil which usually results in hair loss. Now the risk is lower so not sure whether you'd
Im a very lucky gal whose cancer was caught early (by accident) at stage 1c. I've had surgery and about to start chemo tomorrow. Carbopentin only. They booked me a cold cap as I was originally going to have Carbo + Taxil which usually results in hair loss. Now the risk is lower so not sure whether you'd
Shluggie
in
My Ovacome
1 month ago
Are there any contraindications when taking LDN and Ativan?
Are there any contraindications when taking LDN and Ativan? Answered by Pharmacist Stephen Dickson, LDN Specialist Check out www.ldnrtevents.com for LDN Webinars, The LDN Book 3, eBooks, Medical Membership, etc. Please visit our website https://www.ldnresearchtrust.org which is packed with information
Are there any contraindications when taking LDN and Ativan? Answered by Pharmacist Stephen Dickson, LDN Specialist Check out www.ldnrtevents.com for LDN Webinars, The LDN Book 3, eBooks, Medical Membership, etc. Please visit our website https://www.ldnresearchtrust.org which is packed with information
Shewulf
Administrator
in
LDN Research Trust
2 months ago
unknown
I have been dealing with a skin condition for almost 3 years. I have seen other posts like mine. One person was even trying to get on a talk show. I too have been dismissed by health providers. I have had one person mention Reactive perforating collagenosis (RPC) Reactive perforating collagenosis (RPC
I have been dealing with a skin condition for almost 3 years. I have seen other posts like mine. One person was even trying to get on a talk show. I too have been dismissed by health providers. I have had one person mention Reactive perforating collagenosis (RPC) Reactive perforating collagenosis (RPC
Mystery20
in
MY SKIN
2 months ago
I Got Rid Of 90% Of My Dandruff/Seborrheic Dermatitis With One Simple Change (ditch yeast)
I have been off wheat for over a year, but the last few weeks I have been having sourdough bread. I think I will stop. I want to stay away from gluten, lectins, ATI,
and also stay away from yeast
. I stumbled across this video today: I Got Rid Of 90% Of My Dandruff/Seborrheic Dermatitis With
I have been off wheat for over a year, but the last few weeks I have been having sourdough bread. I think I will stop. I want to stay away from gluten, lectins, ATI,
and also stay away from yeast
. I stumbled across this video today: I Got Rid Of 90% Of My Dandruff/Seborrheic Dermatitis With
Bolt_Upright
in
Cure Parkinson's
2 months ago
The RLS nightmare
My name is Tim and RLS sucks!!!!! In 2013 i was put on disability because I have flat back syndrome and it has caused chronic pain for over 20 years non stop 24/7 and I am addicted to opioids. On June 20th of this yr I received a dbl laminectomy on my l4 and l5 vertebra and the knife was removed. Now
My name is Tim and RLS sucks!!!!! In 2013 i was put on disability because I have flat back syndrome and it has caused chronic pain for over 20 years non stop 24/7 and I am addicted to opioids. On June 20th of this yr I received a dbl laminectomy on my l4 and l5 vertebra and the knife was removed. Now
Miloboy23
in
Restless Legs Syndrome
2 months ago
Hair Loss on Acalabrutinib
Has anyone suffered significant hair loss while taking this drug? Does the hair loss stop at some point in time. Does the hair regrow? This is the one thing the oncologist said wouldn't happen. I have been taking an iron supplement and 5,000 mcg of biotin, information that I read in other posts. My hair
Has anyone suffered significant hair loss while taking this drug? Does the hair loss stop at some point in time. Does the hair regrow? This is the one thing the oncologist said wouldn't happen. I have been taking an iron supplement and 5,000 mcg of biotin, information that I read in other posts. My hair
Vinweesel2023
in
CLL Support
2 months ago
reaction to carboplatin
I’m on my second recurrence and currently on carbo/gemcitabine.. ive had a reaction on last three cycles each one being harder than the last.. my question is has this happened to anyone else and , if so what was was the outcome? It’s been mentioned they may slow carb infusion over Two hour period
I’m on my second recurrence and currently on carbo/gemcitabine.. ive had a reaction on last three cycles each one being harder than the last.. my question is has this happened to anyone else and , if so what was was the outcome? It’s been mentioned they may slow carb infusion over Two hour period
SKpaints1
in
My Ovacome
3 months ago
ADT and crying
Does anyone else that has been on ADT drugs for years have trouble with tears or crying for no real reason? I tear up anymore at just the thought of something sad. It’s a major pain in the ass, not to mention embarrassing because I am still employed. Wondering if there is a solution other than stopping
Does anyone else that has been on ADT drugs for years have trouble with tears or crying for no real reason? I tear up anymore at just the thought of something sad. It’s a major pain in the ass, not to mention embarrassing because I am still employed. Wondering if there is a solution other than stopping
joeguy
in
Advanced Prostate Cancer
3 months ago
Zanubrutinib and hair loss?
Hello and Happy Holidays to all! After almost 5 years post captivate trial, I will likely start Zanubrutinib in February or March. My specialist suggested taking Simvastatin in combination with Celebrex experimentally for a couple of months to see if my numbers remain stable. If not, then I will begin
Hello and Happy Holidays to all! After almost 5 years post captivate trial, I will likely start Zanubrutinib in February or March. My specialist suggested taking Simvastatin in combination with Celebrex experimentally for a couple of months to see if my numbers remain stable. If not, then I will begin
fell
in
CLL Support
3 months ago
Picking
My husband with PD has been picking at his skin. Especially his hands. Dermatologist recommended lotions for dry skin. Neurologist says it’s not due to PD. He thinks he is peeling skin, but I don’t see anything. Seems to me to be more like a habit, like biting nails. Has anyone else had this feeling?
My husband with PD has been picking at his skin. Especially his hands. Dermatologist recommended lotions for dry skin. Neurologist says it’s not due to PD. He thinks he is peeling skin, but I don’t see anything. Seems to me to be more like a habit, like biting nails. Has anyone else had this feeling?
Shirleyam
in
Cure Parkinson's
3 months ago
buprenorphine study
Just wondering what people think about the recent study below? Study population was people with opioid use disorder (OUD) who are taking buprenorphine to manage it. Apparently an unusually high percentage of participants had RLS symptoms. I thought Bup alleviated symptoms? I’m in the process of getting
Just wondering what people think about the recent study below? Study population was people with opioid use disorder (OUD) who are taking buprenorphine to manage it. Apparently an unusually high percentage of participants had RLS symptoms. I thought Bup alleviated symptoms? I’m in the process of getting
707twitcher
in
Restless Legs Syndrome
3 months ago
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