Health update: I can live with the news from Roswell this week.
The scans show that growth is starting, but only a small amount so far. I will stay on Tagrisso for another 3 months with the realization that the next scan will probably officially show progression.
My doctor and I updated our treatment plan. In 3 months time, we plan to do a surgical biopsy to remove a lymph node (she has already identified one of interest) to send for Foundation One comprehensive molecular testing. I may go to standard carboplatin/permetrexed chemo at that time, the Foundation One test may reveal another target we can go after, or there may be a new phase 1 trial that would be a good choice. A lot will depend on timing - getting into a good phase 1 trial is a matter of being in the right place (both geographically and disease status) at the right time. It sounds like there might be something completely new making its way into the pipeline for people with my particular subtype of mutation-driven cancer, but I don't know any details yet - my doctor is not yet ready to disclose details of this new trial.
So onward to live the heck out of the next 3 months. I feel like I can actually make plans for the fall!