How long before Cymbalta works for pain?

[SueJohnson]

How long before Cymbalta works for pain?

[red1309]

I experienced relief in about 2 weeks, however, after taking Cymbalta for 14 years, I developed severely high histamine levels and became extremely sick. Please be cautious taking long-term 💜

[SueJohnson in reply to red1309]

Actually I stopped after 3 days as I have restless legs syndrome and take gabapentin and they interacted badly causing my restless legs to flare up.