Hi, I asked my GP what I could do for pain management for endometriosis (I have stage IV, now awaiting MRI scan before next steps).
He gave me a prescription for amitriptyline (10mg/day). I read online that it is handy to take it about 3hrs before bedtime because it can make you drowsy, so this way you're less sleepy in the morning. Also, it said it can take about 2 weeks to work.
Update - 2 wks later - the amitriptyline seems to be helping the strange deep pulling feeling, which I think is the adhesion from my uterus to rectum. It makes the pain a bit more distant, and in the evening when I take it, I feel slightly more cheerful. I had a chat with an endo nurse today, and she suggested increasing to 20mg per day.
Update - after 2 wks, increased to 20mg/day. Last night, I added another 10mg/day. This morning, wow, I was so sluggish! Then a migraine. Now, the migraine is over, and I feel like a sloth... But not in pain! Yay! (I'm also on 400mg ibuprofen 3x a day and omeprazole 20mg/day to protect stomach). Now, I hope the side effects will settle this week so I can be me again. Fingers crossed!
Update: after 3 weeks, with the last week at 20mg/day. I had an adverse reaction (fast, pounding heart, nausea, weakness, dizziness). The doctor advised me to stop taking amitriptyline due to the adverse reaction. Oh well, it wasn't for me.
Has anyone else tried amitriptyline, and did it work for you?