C peptide normal range for Type 1 Diabetes

[ykhalifa]

My 2 years old daughter was diagnosed last September with Type 1 Diabetes, her C peptide value was 1.2 at that time. 3 months later we did the same check and her C peptide was 2.4

is that normal for Type 1 Diabetes?

[nbreight]

found this emedicine.medscape.com/arti...

«C-peptide is a peptide composed of 31 amino acids. It is released from the pancreatic beta-cells during cleavage of insulin from proinsulin. It is mainly excreted by the kidney, and its half-life is 3-4 times longer than that of insulin.

The reference range of C-peptide is 0.8-3.1 ng/mL (conventional units), or 0.26-1.03 nmol/L (SI). [1] »

From the range you mentioned, you have gotten the ng/mL values.

Next page emedicine.medscape.com/arti... mentions several possible causes of increased C-peptide but none of them would make sense for a 2 yr old T1.

One thing it might however point to is Chronic kidney disease. How well is your daughter responding to the insulin therapy? In other words, how certain are you your daughter actually has diabetes type 1?

[nbreight]

Okay, to help answering the question a couple more specific questions:

-1- Does your daughter have a lot of hypoglycaemias?

-2- IF NOT how much insulin are you giving her?

Here are some general indications about dosage ( drugs.com/dosage/insulin-re... )

- 0.5 to 1 UI / kg / day

- if in a remission phase (much) less then 0.5 UI / kg / day

[Activity2004 Administrator in reply to nbreight]

All diabetics are not the same. The doctor may have to decrease or increase the dose for insulin.