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Ancient Ayurvedic scholars have grouped Madhumeh (Diabetes mellitus) under one among the 20 Prameha (urinary disorders); particularly one of the kind of vatic disorder. Also, any of the prameha (urinary disorder) if neglected ultimately it ends up in madhumeh due to nature of the illness. This is evident in the verses of Acharya Sushruta-
सर्व एव प्रमेहास्तु कालेनाप्रतिकारिणः।
मधुमेहत्वं आयांति तदा असाद्यता भवन्ति हि॥(सु. नि. ६)