Insulin-Producing Cells Made in the Liver

All along we had believed that insulin is produced in pancreatic cells. According to University of Technology Sydney Australia, news article, UTS professor Ann Simpson developed the insulin-producing cells, known as “Melligen” cells, with colleagues. The 20-year project has focused on coaxing insulin production from the liver. Simpson says that the idea behind her research came when she realized that the pancreas and liver have similar biological makeup. She believed there was a way to activate liver cells so that they could act like insulin-producing cells in the pancreas.

It appears Nuvilex, a biotechnology company has , purchased the rights to the cells and will be working to get the product on the market in the U.S., Australia, and Europe.

This article is published and can be read on line

2 Replies

  • it is a ray of hope if it works.

  • As islet cell transplant is not very successful with so much of limitations,different researchers are trying for an alternative. So they looked at liver which has so much structural similarity and in many primates they have only one organ which functions both as liver and kidney.

    Now they take out liver cells and propagate it in the lab. In these propagated cells ,a master gene is added which converts liver cells into what they call Autologous Insulin Producing cells.These cells are put back into liver, where they start producing insulin.

    It's only a hope that some day in future it can be effectively used on humans to de feat diabetes. Let us hope for the best.

You may also like...