I understand that the drug Pioglitazone (Pi... - Diabetes India
I understand that the drug Pioglitazone (Piosys) is about to be banned. What is the alternative? I've been taking with Glycipage and Isryl.
Please talk to your doctor.There are alternative combinations.
The drug is banned in India. By a notification on 18 June 2013, Indian government has suspended manufacture and sale of this drug in India with immediate effec The side effects of this medication is heart failure and bladder cancer.
Metformin is used alone or with other medications, including insulin, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Metformin is in a class of drugs called biguanides. Metformin helps to control the amount of glucose (sugar) in your blood. It decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. Metformin also increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood.
The most common side effects with metformin (generic name) Glyciphage (brand name) are nausea, vomiting, gas, bloating, diarrhea and loss of appetite. These symptoms occur in one out of every three patients. These side effects may be severe enough to cause therapy to be discontinued in one out of every 20 patients. These side effects are related to the dose of the medication and may decrease if the dose is reduced.
A serious but rare side effect of metformin is lactic acidosis. Lactic acidosis occurs in one out of every 30,000 patients and is fatal in 50% of cases. The symptoms of lactic acidosis are weakness, trouble breathing, abnormal heartbeats, unusual muscle pain, stomach discomfort, light-headedness and feeling cold. Patients at risk for lactic acidosis include those with reduced function of the kidneys or liver, congestive heart failure, severe acute illnesses, and dehydration.
Glimepiride is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Glimepiride lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally.
Common side effects of glimepiride include dizziness, headache, and nausea or vomiting. A rash and allergic reactions also may occur. Low blood sugar (hypoglycemia) can occur during glimepiride therapy. Symptoms of low blood sugar include hunger, nausea, tiredness, perspiration, headache, heart palpitations, numbness around the mouth, tingling in the fingers, tremors, muscle weakness, blurred vision, chilliness, excessive yawning, irritability, confusion, or loss of consciousness.
Glimepiride is a derivative of a sulfonamide drug. People allergic to other sulfonamide-related drugs may develop an allergic reaction to glimepiride.
Change of lifestyle by diet and exercise is better than anti-diabetic medications.
Consult your doctor.
Sources:--
en.wikipedia.org/wiki/Piogl...
medicinenet.com/pioglitazon...
nlm.nih.gov/medlineplus/dru...
medicinenet.com/metformin/a...
en.wikipedia.org/wiki/Metfo...
medicinenet.com/glimepiride...
en.wikipedia.org/wiki/Glime...
nlm.nih.gov/medlineplus/dru...
Thanks Mr. Gangadharan Nair. It is quite informative and should be read by one and all.
