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Experiences with
Degarelix
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Rising PSA on ADT
Degarelix
for 8 months. Two months after end of
Degarelix
PSA rising rapidly (doubling time 5 weeks). Started ADT (Zoladex) Feb 2023. By Oct PSA 0.40 ug/L, Dec 0.43 ug/L, Feb 2024 0.46 ug/L.
Small rises but still on Zoladex.
Degarelix
for 8 months. Two months after end of
Degarelix
PSA rising rapidly (doubling time 5 weeks). Started ADT (Zoladex) Feb 2023. By Oct PSA 0.40 ug/L, Dec 0.43 ug/L, Feb 2024 0.46 ug/L.
Small rises but still on Zoladex.
MGBman
in
Advanced Prostate Cancer
2 months ago
Barry
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly
degarelix
injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly
degarelix
injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
littlemount
in
Advanced Prostate Cancer
2 months ago
Gummie relief for degarelix shots?
DH has so much pain with each monthly shot and can't take nsaids. Is there anything that won't make him loopy to use after shots for a few days? He is ready to go back to lupron, it hurts so much. Mail order preferred.Thanks!
DH has so much pain with each monthly shot and can't take nsaids. Is there anything that won't make him loopy to use after shots for a few days? He is ready to go back to lupron, it hurts so much. Mail order preferred.Thanks!
Chipnick
in
Advanced Prostate Cancer
27 days ago
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Finasteride: "Miracle drug" regrows hair, heals prostate, and also boosts heart health ByEric Ralls Earth.com
I am now thinking to add Finasteride to Bicalutamide plus
degarelix
injections. Would/could it help me if on the psma pet scan my only visible cancer is in my prostate?
I am now thinking to add Finasteride to Bicalutamide plus
degarelix
injections. Would/could it help me if on the psma pet scan my only visible cancer is in my prostate?
Seasid
in
Advanced Prostate Cancer
1 month ago
Degarelix and increased diabetes risk?
Has anyone developed diabetes after starting
Degarelix
?
Has anyone developed diabetes after starting
Degarelix
?
Oatmeal2
in
Prostate Cancer Network
6 months ago
Arrythmias on Zytiga
Or just finish the 24 months with ADT (
degarelix
).? Abiraterone ends march 1, 2024. So I’d be 5 months short.
Or just finish the 24 months with ADT (
degarelix
).? Abiraterone ends march 1, 2024. So I’d be 5 months short.
Oceankayaker
in
Advanced Prostate Cancer
6 months ago
degarelix v/s eligard "lupron"
Eligard to allow for a long cruise .now that I am back home I decided to go back on
degarelix
with its 28 day cycle .With the help of aberaterone my psa has remained at.014for the last 10 months.My question is this wise to continue with
degarelix
I notice most of you brothers are getting lupron l
Eligard to allow for a long cruise .now that I am back home I decided to go back on
degarelix
with its 28 day cycle .With the help of aberaterone my psa has remained at.014for the last 10 months.My question is this wise to continue with
degarelix
I notice most of you brothers are getting lupron l
yardsailor
in
Advanced Prostate Cancer
6 months ago
Chemo or no/not yet?
PSA hit 366 before starting Abiraterone and
Degarelix
. Start Lupron next week. Negative on DNA test. Will see what PSA looks like next week after a month of ADT. My question chemo, no chemo or wait on chemo? Onco and Rad Onco both seemed to have a very soft attitude towards it.
PSA hit 366 before starting Abiraterone and
Degarelix
. Start Lupron next week. Negative on DNA test. Will see what PSA looks like next week after a month of ADT. My question chemo, no chemo or wait on chemo? Onco and Rad Onco both seemed to have a very soft attitude towards it.
4tunate1
in
Advanced Prostate Cancer
9 days ago
Degarelix bad reaction
I just had my 5th
Degarelix
injection. The prior four injections prompted no reaction beyond pain and soreness at the site. The reaction to the 5th shot caused more pain than usual at the injection site, but also came with chills and severe joint and muscle pain by that evening.
I just had my 5th
Degarelix
injection. The prior four injections prompted no reaction beyond pain and soreness at the site. The reaction to the 5th shot caused more pain than usual at the injection site, but also came with chills and severe joint and muscle pain by that evening.
NewGame
in
Advanced Prostate Cancer
7 months ago
Agonists vs. antagonists (the latter not to be confused with a character in a novel!)
I know many of you on this site are beyond ADT, but for those who are still holding on in that space, I'd like to share my experience with the newer antagonists drugs,
degarelix
( U.S. brand, Firmagon) and relugolix (U.S. brand, Orgovyx).
I know many of you on this site are beyond ADT, but for those who are still holding on in that space, I'd like to share my experience with the newer antagonists drugs,
degarelix
( U.S. brand, Firmagon) and relugolix (U.S. brand, Orgovyx).
bluesnjazz
in
Advanced Prostate Cancer
2 months ago
Extreme sweats will they diminish; Zitiga is it worth it
I started treatment with initial "double load"
Degarelix
shot July, 2023. My MO retired and the new MO changed from
Degarelix
to Lupron, the 3 month shot, August, 2023 to be more convenient rather than having to come in every 28 days for the
Degarelix
shot.
I started treatment with initial "double load"
Degarelix
shot July, 2023. My MO retired and the new MO changed from
Degarelix
to Lupron, the 3 month shot, August, 2023 to be more convenient rather than having to come in every 28 days for the
Degarelix
shot.
Falcon10
in
Advanced Prostate Cancer
7 months ago
Too many vitamins ?
I am now on Erleada and
degarelix
feeling much better and with the regular side effect of hot flashes and tireness. I took for 8 years and still now the following supplements : Resverstrol, coenxymeQ10 ,K2 , D3 ,B12 , D, Complex B50 , Lycopene, Calcium ,Tumeric ,C.
I am now on Erleada and
degarelix
feeling much better and with the regular side effect of hot flashes and tireness. I took for 8 years and still now the following supplements : Resverstrol, coenxymeQ10 ,K2 , D3 ,B12 , D, Complex B50 , Lycopene, Calcium ,Tumeric ,C.
Raminagrobis
in
Advanced Prostate Cancer
6 months ago
Neuroendocrine PCa
After 6 rounds of doxitacel, enzulamite and
degarelix
. The doctor has said chemo + immunotherapy. And given us 9-12 months. Is that really it ?
After 6 rounds of doxitacel, enzulamite and
degarelix
. The doctor has said chemo + immunotherapy. And given us 9-12 months. Is that really it ?
Priyamvada91
in
Advanced Prostate Cancer
8 months ago
de novo metastatic prostate cancer
I’ve been on
degarelix
/Firmagon and Abiraterone for the past 3.5 months and it seems to be working well - just had my 3 month scans. And the terrible fatigue is under control. Anyone else on these two drugs? What’s your long term experience been? thanks Robert
I’ve been on
degarelix
/Firmagon and Abiraterone for the past 3.5 months and it seems to be working well - just had my 3 month scans. And the terrible fatigue is under control. Anyone else on these two drugs? What’s your long term experience been? thanks Robert
NewGame
in
Advanced Prostate Cancer
8 months ago
Worry: Running Bounces Degarelix Stomach Depot
QUESTION: Is anyone aware that
the stomach subcutaneous
drug depot could be affected by jostling? There are lots of reasons why after a while people become castrate resistant.
QUESTION: Is anyone aware that
the stomach subcutaneous
drug depot could be affected by jostling? There are lots of reasons why after a while people become castrate resistant.
JohnInTheMiddle
in
Advanced Prostate Cancer
9 months ago
QOL: summer cruise on the coast of Maine
Tomorrow I start
Degarelix
injections once again after being on a three month leuprolide depo-formulation ,I am thankful for those sweet summer days, but I think it better to go back to a monthly injection and regular visits with my MO. And so my brothers my voyage continues
Tomorrow I start
Degarelix
injections once again after being on a three month leuprolide depo-formulation ,I am thankful for those sweet summer days, but I think it better to go back to a monthly injection and regular visits with my MO. And so my brothers my voyage continues
yardsailor
in
Advanced Prostate Cancer
6 months ago
PSA increase nearly one year after triplet therapy (mHSPC), what's next?
Edit: If that is any interest, he couldn't handle monthly injections of
Degarelix
(Firmagon) so he switched to Decaptetyl (Triptorelin) every 3 months and his PSA actually dropped further. Not sure if it's related though.
Edit: If that is any interest, he couldn't handle monthly injections of
Degarelix
(Firmagon) so he switched to Decaptetyl (Triptorelin) every 3 months and his PSA actually dropped further. Not sure if it's related though.
Sissel25
in
Advanced Prostate Cancer
4 months ago
PSA rising on Triplet Therapy after <18m
He began triplet therapy (initially
degarelix
, then leuprolide + abiraterone and prednisone) soon after. By September it had fallen to under 0.1 and then under 0.05 by the summer of 2023. Subsequent PET scans showed some bone mets had shrunk, others were unchanged.
He began triplet therapy (initially
degarelix
, then leuprolide + abiraterone and prednisone) soon after. By September it had fallen to under 0.1 and then under 0.05 by the summer of 2023. Subsequent PET scans showed some bone mets had shrunk, others were unchanged.
nyc_son
in
Advanced Prostate Cancer
1 month ago
Prostate Cancer (stage IV) identified in January and Small Cell Carcinoma (Neuro endocrine) in liver in August. Any suggestions?
He was put on Abiraterone and
Degarelix
. In August, PSA test showed that PSA had dropped to 2.7 and there was decrease in size and PSMA avidity of Prostate lesion. But, PSMA PET CT in August found mildly PSMA avid lesion in liver, which was not seen in the PSMA PET CT five months back.
He was put on Abiraterone and
Degarelix
. In August, PSA test showed that PSA had dropped to 2.7 and there was decrease in size and PSMA avidity of Prostate lesion. But, PSMA PET CT in August found mildly PSMA avid lesion in liver, which was not seen in the PSMA PET CT five months back.
RindaMan
in
Advanced Prostate Cancer
7 months ago
Increased risk of dementia with ADT, especially Degarelix?
Hi everyone, my first post! A friend sent me the below earlier. Looks worrying on the face of it. I'm not great with trial data, so would appreciate the views of those more knowledgeable, especially Tall_Allen. https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144860
Hi everyone, my first post! A friend sent me the below earlier. Looks worrying on the face of it. I'm not great with trial data, so would appreciate the views of those more knowledgeable, especially Tall_Allen. https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144860
john510185
in
Advanced Prostate Cancer
10 months ago
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