This is hopefully the tweet link but not sure if linking tweets is allowed!
twitter.com/AlbertoEspay/st...
"(8/8) Trials in #Parkinsons do not test hypotheses; they just help us "learn." The lessons learned (with editorial endorsement) are future longer trials and/or targeting prodromal patients.
The toxic proteinopathy hypothesis again emerged unscathed."
Dr Espay's recent silver bullet talk covers the same ground with more detail and was an eye-opener for me