UC Davis, China find may alleviate neuroi... - Cure Parkinson's

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UC Davis, China find may alleviate neuroinflammation in Parkinson’s disease

Gibberesh profile image
23 Replies

Found this: "Their novel research, published in the current edition of the Proceedings of the National Academy of Sciences, shows that a soluble epoxide hydrolase (sEH) inhibitor and kurarinone, a compound from the dried root of Sophora flavescens, reduced neuroinflammation in an animal model with Parkinson’s disease. The dried root, also known as kushen, has been used for hundreds of years in traditional Chinese medicines." From: msn.com/en-us/health/medica...

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Gibberesh profile image
Gibberesh
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23 Replies
Gibberesh profile image
Gibberesh

Found you can buy here: amazon.com/Flavescens-Cardi...

park_bear profile image
park_bear

Abstract here:

pubmed.ncbi.nlm.nih.gov/352...

Not clear whether the substance was applied as pretreatment or posttreatment with respect to the toxicant.

ghoegap profile image
ghoegap in reply to park_bear

Hi ! If you do discover how and when the substance was applied please do advise us , thanks thanks for all your input

Has anyone used this version? It was recommended by someone on HU. I’m hoping to find an ideally 3rd party tested reputable source.

tcmzone.com/product/ts59/

House2 profile image
House2

I used it in the form of Ku Shen Tea. It helped better than anything including C/L. I had to stop it :( due to my hypotension. I actually felt like me again, until my blood pressure cratered. It is a MAOb inhibitor also.

in reply to House2

Amazing. I’m sorry you weren’t able to continue. Is the site I posted where you bought it from? Requires me to register. Have you tried licorice root? It does not lower blood pressure.

in reply to House2

Do you think it’s main benefit is it’s being a MAOB inhibitor? Do you take Azilect? I do and I can tell no difference

House2 profile image
House2 in reply to

herbs tend to modulate multiple pathways, so it's hard to tell. I'm on blood thinners now, so as far as herbs go, I'm dead in the water.

in reply to House2

Did the hypotension cause the AFib? And do you think the PD caused the hypotension? I have very low blood pressure, dizziness, etc and it’s hard to differentiate sometimes between internal tremors and heart palpitations. How do you ensure adequate blood flow to the brain? That is a big concern of mine and I’m assuming most PWP. I take Vinpocetine for this purpose. Between the dizziness and the cramps and the soreness I often feel like a mess but it’s all invisible so I just try and “act normal.”

Despe profile image
Despe in reply to

CC,

Are you using magnesium oil for your cramps? I don't remember when was the last time hubby had any cramps. I spray mag oil on his legs every single night, it works wonders.

in reply to Despe

Thank you Despe, 😊 my cramps have changed and are mostly goofy toe cramps. I should try it on my toes? Maybe it will help. Oddly enough ice baths help

Are you interested in this Ku Shen tea?

Despe profile image
Despe in reply to

Yes, mag oil will work anywhere, it's worth trying it. Taking ice baths? Whole body or just feet?

I am not sure about this tea. I have to read about it. . .

Kia17 profile image
Kia17 in reply to

CC

Does your toes cramp start while doing activities like walking, running, stretching or at rest?

in reply to Kia17

They twitch on their own when I’m sedentary or standing but not moving. Most frequent issue is my feet “fall asleep” while I’m exerting myself like jumping on a trampoline, running, riding a bike. How on earth they can tingle and go numb while I’m exercising vigorously alludes me and my GP. The cramping is less frequent but more bothersome and happens very randomly. Thank you for asking. My list of symptoms is very long but all are mild. But they function like at unwanted dysfunctional symphony.

Kia17 profile image
Kia17 in reply to

When you intentionally contract your leg muscles, glutes, hamstring or other lower extremity muscles like isometric exercises , do you completely feel those muscle are contracting? What is you toes reaction when you do so? Do your toes tend to stay away from each other, do they flex , extend? Thank you

in reply to Kia17

I think my muscles fully contract. I jog , hike, etc. When I flex my toes don’t do anything different, they just sit there. I’m very curious about your inquiries. Sure with my doc new or cared about what to ask.

Kia17 profile image
Kia17 in reply to

I think some of your muscles are inhibited (the main ones are glutes) and your hip flexors and psoas muscles are shortened. When you have time lying on your back (supine position) in relax position try to contract your glute muscle and other lower body muscles ONE by ONE and see if you can contract them without any compensation using other muscles. While doing these try to observe your toes. Keep us posted please, if that’s the case I have some exercises to help the toes dystonia.

House2 profile image
House2 in reply to

FYI. ncbi.nlm.nih.gov/pmc/articl...

House2 profile image
House2 in reply to House2

FYI2 frontiersin.org/articles/10...

Ghmac profile image
Ghmac in reply to House2

Where did you get your Ku Shen Tea? And did you like the taste?

House2 profile image
House2 in reply to Ghmac

tcmzone.com/product/ts59/

Sydney75 profile image
Sydney75

Thanks, on the look out for a tea, think its a more benign way to try a new supplement.

House2 profile image
House2 in reply to Sydney75

Warning: tastes Really Bad!!!

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