37 articles on various neuroprotective ag... - Cure Parkinson's

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37 articles on various neuroprotective agents

Bolt_Upright profile image
13 Replies

37 articles on various neuroprotective agents:

frontiersin.org/subjects/ne...

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Bolt_Upright
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Great link Bolt! I recently wrote about L Serine if you are interested in that one.And Moringa as an alternative to broccoli as an NRF2 activator.

Regarding Metformin, I recommend researching Berberine instead.

Ginko I recommended by Dr. Dale Bredesen. It lowers blood pressure (if I remember correctly) which is why I’m not personally pursuing it.

Another one that is worthy of the list is Bacopa.

Many on there to dig in to! 😊

Off to have my Bolt Licorice.

Bolt_Upright profile image
Bolt_Upright in reply to

I take Berberine. I am starting to think it helps. Thanks chartist !

Smittybear7 profile image
Smittybear7

Thanks for sharing

Smittybear7 profile image
Smittybear7

How do you know how much to use? Where can you purchase them? Is lithium a prescription? Thanks for your help

CaseyInsights profile image
CaseyInsights in reply to Smittybear7

You can start here - 5mg Lithium Orotate

amazon.com/Weyland-Lithium-...

My spouse use 10mg at present.

Smittybear7 profile image
Smittybear7 in reply to CaseyInsights

What does lithium help?

CaseyInsights profile image
CaseyInsights in reply to Smittybear7

My spouse began using - at my suggestion - as a hedge against potential memory issues. The effect (2/3 months later) was a reduction in anxiety.

But it is good for a ton of stuff. This $10 kindle book has all the reasons why it should be in your arsenals of supplements.

amazon.com/dp/B01FT4OGDI/re...

P.S: I had first ordered a 5mg and a 10mg bottle. This is over a year ago. Since then I have used 10mg. The next order is going to be for 20mg. I use it in my night stack.

CaseyInsights profile image
CaseyInsights

...and here is a paper of an unsung vitamin and an largely unrecognized pathway

Riboflavin Has Neuroprotective Potential: Focus on Parkinson’s Disease and Migraine

Unsung Vitamin: B2 (Riboflavin)

Unrecognized Pathway: Tryptophan-Kynurenine Pathway

The authors conclude -

Indeed, riboflavin ameliorates oxidative stress, mitochondrial dysfunction, neuroinflammation, and glutamate excitotoxicity; all of which are involved in the pathogenesis of a wide range of neurological disorders.

In addition, riboflavin is required for pyridoxine (B6) activation. Riboflavin and PLP, the active form of pyridoxine, play essential roles in homocysteine metabolism, and tryptophan-kynurenine pathway.

Indeed, any accumulation of homocysteine or kynurenines due to vitamin insufficiency can lead to significant neurological consequences.

The paper is a bit of a slog to read. But I would suggest that you do explore the diagrams for a quick insight and as a jump off point for further research if so desired.

frontiersin.org/articles/10...

Smittybear7 profile image
Smittybear7 in reply to CaseyInsights

Thanks

Smittybear7 profile image
Smittybear7 in reply to CaseyInsights

How do you determine the amount of riboflavin to take?

CaseyInsights profile image
CaseyInsights in reply to Smittybear7

Riboflavin is usually used as a prophylaxis for migraine.

The dosage suggested is 400mg. And that's where I started. Used 30 tablets with no noticeable effect or side effects. But I am pushing forward.

Currently have 60 Riboflavin tablets ( 400mg) and 60 Riboflavin 5 Phosphate capsules (36.5mg) and I plan to alternate them over a 120 day period.

The Riboflavin 5 Phosphate is the bio-available version of Riboflavin (B2)

Will begin this experiment soon to see if any thing noticeable happens.

P.S: If you take a good B-Complex you will have at least 50 mg of Riboflavin per capsule.

Fumaniron profile image
Fumaniron

You are a good dude, Bolt_Upright!

Gcf51 profile image
Gcf51

Great Link... Many things to ponder...

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