Taking high-dose melatonin: I've been... - Cure Parkinson's

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Taking high-dose melatonin

mrvl profile image

I've been taking around 157 mg of melatonin daily. Just for the health benefits.

My question is. Should I take it all at once, or throughout the day? Presently I'm taking 42 mg when I wake up and 42 before bed. I take another 15 mg, 5 times during the day.

15 Replies

mrvl,

I am curious as to how you arrived at that dose and how long you have been taking it?

I take it at 106+ mg/night and take it only in the evening spread out as well as I can. The highest I have been is 180 mg/night. Taking it during the day, I reserve for acute and severe illness. Taking it during the day time can disrupt multiple circadian rhythms in the body and might not be a good idea over the long term.

Art

mrvl profile image
mrvl in reply to chartist

I did some reading on Melatonin, because my wife was on chemo for colon cancer.

I liked how it helped the chemo killed a bad cancer cells and help the good cell survive. So she took melatonin.

I had Labs coming up in 52 days, so I just thought I would try melatonin, for 52 days. My labs were the best I ever had. My doctor was blown away.

So I continue taking it, for another 6 months and we'll have labs this coming Tuesday. I'm doing it kind of blind. So that's why I'm asking.

chartist profile image
chartist in reply to mrvl

I've been at my current dose for just shy of a year. I have written extensively about melatonin on this forum for multiple health issues. Here are some links to what I have written about its use for health :

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

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healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

Art

mrvl profile image
mrvl in reply to chartist

Thanks for the reply. I will go through all the threads, that you have worked on.

rhyspeace12 profile image
rhyspeace12 in reply to mrvl

It stopped my husband's sun downing.

Dragona profile image
Dragona in reply to rhyspeace12

Hello my dad has terrible sun downing can you tell me the dose he takes and what time of day please

mrvl profile image
mrvl in reply to Dragona

I'm new to this platform and just learning about melatonin. there are members much more knowledgeable than me. From what I read, I believe he should take 10 mg of melatonin at 4:00 p.m. and then another 10 mg of melatonin before bed. Hopefully someone else would chime in and give you good information.

rhyspeace12 profile image
rhyspeace12 in reply to Dragona

I figured it out by myself. My husband has since passed away from Parkinson's complications, but he was sun downing terribly, to the point where he ended up with hypothermia when found laying in a field on our property for hours after leaving the house during the night.I started giving him 10 mg at 4 pm and another 10 mg at 10 pm. The only time it failed after that was when my son forgot to give him his first dose until 6 pm. You just have to start it before the sun goes down. Perhaps you will have to adjust his dose, but I have never heard of Melatonin hurting anyone.

mrvl profile image
mrvl in reply to chartist

After reading over some of the threads. It sounds like, it's better to take melatonin at night. To keep my natural sleep rhythm. I'm wondering if I can just start dosing early evening and until I go to bed? Any thoughts on this.

chartist profile image
chartist in reply to mrvl

That is what I do and that is what the body does, secretes melatonin as daylight turns to night. So you are essentially trying to replicate the action of the pineal gland which is affected by light exposure. Avoiding too much artificial light at night is helpful because light exposure works against melatonin secretion and I believe it tends to stop melatonin secretion just as morning sunlight does. The bright morning sunlight exposure outside helps maintain the circadian rhythm by telling the body it is daylight and time to get up and be active.

Art

chartist profile image
chartist in reply to mrvl

mrvl,

I would be interested in hearing your lab results when they come available.

Art

How on earth do you stay awake?

mrvl profile image
mrvl in reply to Nitro53

It doesn't make me tired. I think you need a lower dose for sleep, I get that from a lot of people, how can you take so much melatonin and stay awake.

akgirlsrock profile image
akgirlsrock in reply to mrvl

How has it with Parkinsons? Thank you

mrvl profile image
mrvl in reply to akgirlsrock

I don't have Parkinson's. It sounds like, that they give someone with Parkinson's 10 mg at 4:00 p.m. and 10 mg at 10:00 p.m. it's better to search the threads. I'm new to studying melatonin.

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