List of nutrients that were tested in clinical trials with outcomes for PD 2021

[Bolt_Upright]

Interesting table 2 in this document google.com/url?sa=t&rct=j&q...

After some good feedback I have decided this is a poorly put together table and I don't actually agree with the oversimplified findings.

[Astra7]

Really interesting table. I note that Creatinine took 18 months to have an impact. I usually try things for 3 months and then give up if no improvement.

[Bolt_Upright in reply to Astra7]

I looked at the creatine minocycline study from 2008. Did not look impressive at all: pubmed.ncbi.nlm.nih.gov/185...

[Hidden]

This is so oversimplified that it is misleading and and counter productive. For example; Omega 3, there is an abundance of evidence to support its importance. To conclude “meh” based on flaxseed oil is really spreading misinformation.

Before saying “meh” to important nutrients such as Omega 3 based off of the wrong form, flaxseed, look in to different forms like krill oil, sardines, wild caught salmon for example.

I’m very concerned about steering people down the wrong path with misinformation.

[PDGal4]

I agree with cclemonade--you need details of studies to make determinations, not simplified tables. Dr. Mischley has said about CoQ10, for example, although the study concluded no real benefits, she feels it helps people with one form of Parkinson's vs. another -- tremor vs. slowness--as presenting symptom, and also helped people more in one stage of the disease than another (sorry, cannot recall which ones she felt benefited more)

[Hidden in reply to PDGal4]

Regarding CoQ10, Ubiquinol is a more bio available form. And as you pointed out, a study showed no benefit but, in who and for how long and in what form and working synergistically with what? Over simplifications lead us in the wrong direction.

Better to say one doesn’t know than give false conclusions.

[Bolt_Upright in reply to Hidden]

And there are analogues (of which Idebenone is one) Coenzyme Q10 Analogues: Benefits and Challenges for Therapeutics ncbi.nlm.nih.gov/pmc/articl...

[Bolt_Upright in reply to PDGal4]

Fixed it. Thanks.

[Hidden]

My husband was recently diagnosed. Our plan is to eventually test him (and me for different but some overlapping issues) for every nutrient under the sun, every biomarker mentioned in the Pubmed studies that might be off with PD, and the functional medical tests type gamut. He has a regular doctor and a neurologist, too, but they don't seem interested in nutrition. We've just been paying for the tests on our own and using walkinlab type place orders. So far we've found he was really low in uric acid and vitamin D, and suboptimal in B12. I bought uric acid test strips on Amazon and he has been getting his UA numbers up with diet changes and feeling better. The vitamin D and B12 have been getting better with diet changes and supplements but are still low.

Since these studies with nutrient deficiencies often have contradictory results when testing large groups of people, it seems unlikely every person with PD has exactly the same deficiencies and may need individualized diet changes or supplements.

[Bolt_Upright in reply to Hidden]

You might want to look at the Bredesen FB group. Their focus is ALZ but they have a lot of ideas and are really nice. I bounce ideas off them frequently. facebook.com/groups/officia...

[Hidden in reply to Bolt_Upright]

I will check them out. I have the Breseden protocol printed out and we've been checking off that list, too.

[Bolt_Upright in reply to Hidden]

Somebody recently shared some links for mail-in labs. Not an endorsement. I have not used them.

lifeextension.com/lab-testi...

ultalabtests.com/shop

[Hidden in reply to Bolt_Upright]

We've used ultalabs, requestatest and walkinlabs. They are all fine and use either Quest or Labcorp for the blood draws. We're retired and live close to both labs so we just use which ever order site is cheaper. They all seem to have frequent sales. Ultalabs has a uric acid test for $13 and that seems to be a really key biomarker many patients with PD are low in. We're finding a lot of overlap with the Wahl Protocol for MS, and what seems to be helping my husband, like organ meat to raise uric acid levels. UA seems to be low in both groups. I bought organic liver from Whole Foods he feel helps.

[Bolt_Upright in reply to Hidden]

Note to self: Eat some organ meat.

It's funny, we always have liver in the freezer as we feed our cat raw liver all the time. I keep forgetting to grab some myself.

I follow a combination of Wahl's Paleo Plus and the Specific Carbohydrate Diet. Well I did for 6 months. Started cheating a little this week. Have my can of coconut milk most days.

[Hidden in reply to Bolt_Upright]

One thing different from Wahl's protocol and the PD research I looked at is that nightshade vegetables seem to be good for PD - peppers, eggplant, tomatoes and potatoes. They are in the same plant group as tobacco and smoking seems to have an inverse relationship with PD. We aren't doing low carb like the Wahl diet but we did reduce lectins based on the PD research about lectins and pesticides. I hadn't heard of Specific Carbohydrate Diet. I will look that up.

Organ meat is high in purines (for urid acid), high in K2, high in B12 and high in CoQ10, so it seems like a good food for PD.

I bought a uric acid meter on Amazon though I haven't tried it yet. The nutritionfacts site says the good spot for uric acid levels is 5 - 7. Ranges below that are linked to PD and Alzheimer's and above that gout and heart disease.

[Bolt_Upright in reply to Hidden]

Good point. I eat tomatoes every day.

[alaynenadelbach]

This table exaggerates the importance of many trace elements. It's necessary to prioritize important trace elements in consumer products differently. Once a month, I try to conduct tests of the food consumed and keep a food diary. When I notice that after certain products, I feel bad, I buy mzfoodtest.com/microbiology... to determine which microelement and product caused such a reaction of the body. The only thing I have established so far is the poor tolerance of lactose and gluten. I'm also thinking about switching to a vegetarian diet, but I'm afraid of a B12 deficiency in the future.

[Hidden]

you have GREAT posts! thank you sir!

[Bolt_Upright in reply to Hidden]

Thank you. I pray I am able to help.