why does an antibiotic improve my PD sym... - Cure Parkinson's

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why does an antibiotic improve my PD symptoms BIG TIME

professor profile image
professor

I WAS GIVEN A N ANTIBIOTIC FOR SKIN IN HOSPITAL

IT GAVE ME A HUGE IMPROVEMENT IN MY PD SYMPTOMS

BUT TTHE DOCTORS POO POOD MY CLAIM

WHICH INDICATES PD ISA VIRUS AND THAATS NEW

56 Replies

Not necessarily, there might be bacteria involved in this. There is much reason to believe so.

professor profile image
professor in reply to GymBag

yeh maybe all i know is i went from 15% MOBILITY TTO 98%I COULD DANCE DO THE HULA HOOP SING NOTHING IN30 YEARS HHAS COME CLOSE .....WE HAVE THE FUCKER BY THE BALLS excuse the french THEANTIBIOTIC IS CLARITHROMYCINBUT THIS MEANS CELLSARE NOT DEAD I HAD FULL NAVIGATION, it is unknown to my

experienced consultant what this is i was given it for a different reason.. ah wonndered what i was hingin on for yu kina loose hope NNOT NOW YU KNOW I THINK WEVE BEEN LED A MERRY DANCE

What antibiotic were you using? Some folks have reported that Doxycycline has temporarily reduced their symptoms. Doxy crosses the blood brain barrier and also reduces the chemokine IL-8, which is inflammatory in overall action. Doxy can also kill multiple bacteria in the gut. If it kills enough pathogenic bacteria in the gut, that may temporarily improve symptoms until those pathogenic bacteria return. The reduction of IL-8 in the brain and cerebrospinal fluid may also be beneficial for PwP, but again, this effect is temporary. Btw, antibiotics are not used for virus, that would be antivirals.

Art

LindaP50 profile image
LindaP50 in reply to chartist

Doxy is the main antibiotic given to folks with Lyme Disease - because its a blood brain barrier.

chartist profile image
chartist in reply to LindaP50

It's not main stream at all, but colloidal silver (AgNP) is synergistic with Doxy and I can only speak for myself, but if I had LD, AgNPs would definitely be part of my regimen to eradicate it! AgNPs also cross the blood brain barrier.

Art

professor profile image
professor in reply to chartist

THIS WAS NOT DOXY THIS WAS AACOMMPLETE RECCOVERY OF MY WALKING SPEAKING I COULLD DANCE I WAS ALMOST INA WHEELCHAIR THIS IS THE PROOF CCELLS ARE NOT DED

chartist profile image
chartist in reply to professor

Well, Doxy requires a prescription and it may be impossible to find a doctor who will write a script for Doxy as a treatment for PD. How long did the benefit last. If I remember correctly, people who have reported such benefit from Doxy, said the effects were short lived.

Art

professor profile image
professor in reply to chartist

YEH THIS HAPPENED TO ME BEFORE WITH A DIFFERENT ANTIBIOTIC I DISSMIISED IT AS HOSPITAL CUSTARD.. WHEN THE CL;ARITHROMYCIN......FINISHED I WAS GOOD FOR ABOUT 2 WEEKS but im sure writings on the wall....

JAS9 profile image
JAS9 in reply to chartist

I remember this being discussed years ago on this forum, but I can't find it now. Recently, we have learned a lot about gut bacteria, the direct connection between the gut and the brain, and how a leaky gut leads to autoimmune diseases and even problems with the brain as well.

My guess - and it is very definitely just a guess - is that you have a leaky gut or SIBO, and your PD might have been caused by, or is being negatively affected by the inflammation it leads to. Basically, you have too much bad bacteria not enough good bacteria in your gut, or good bacteria has gotten into some place that shouldn't be. You need good bacteria and good bacteria need fiber to keep what's in your gut from leaking into your blood.

It's common for people with SIBO and similar problems to experience relief from antibiotics, but wiping all of the bacteria out without doing anything to encourage the good bacteria to grow and thrive is a recipe for disaster. You could end up with any number of autoimmune diseases, which can cause a great deal of inflammation. For example, certain types of arthritis, lupus, and celiac, are autoimmune diseases.

Instead, talk to a specialist who knows what they are doing. For example there are antibiotics that target only bad bacteria in your gut. You can also change your diet to include much more fiber and unprocessed foods to help repair your leaky gut. If my guess is right.

chartist profile image
chartist in reply to JAS9

FMT appears to eradicate SIBO in 12 weeks or less based on the new FMT study. It also eliminated constipation, improved non motor symptoms and motor symptoms significantly in that same time period.

You've got my interest now, what antibiotic targets only bad gut bacteria?

Art

JAS9 profile image
JAS9 in reply to chartist

Rather than give you a list based on my very limited knowledge, I think it's better to refer you to an expert. This guy says that he's not a doctor, and technically that's true, but he is working on a PHD in nutrition and knows more about gut health issues than anyone I've ever come across. Although I'm giving a link to just one video, his Youtube channel has many, many more.youtube.com/watch?v=BuZCR-u...

chartist profile image
chartist in reply to JAS9

JAS,

Based on this video, he is saying to use antimicrobials for certain infections as they are natural antibiotics such as garlic, grapefruit seed extract, berberine, olive leaf extract, astragalus, elderberry extract, curcumin, oregano, rosemary, many essential oils etc. These are generally quite effective in many bacterial infections and some have antiviral activity as well as antiparasitic activity. Colloidal silver, although not quite natural, has broad spectrum antimicrobial, antiviral, and to a lesser extent antifungal and antiparasitic effects. Antibiotics on the other hand are bacterial killers. He doesn't mention any antibiotics that don't also kill good bacteria. He says antibiotics should be reserved for more serious infections and I would agree with that.

Art

MBAnderson profile image
MBAnderson in reply to chartist

Art,

What do you mean by FMT?

chartist profile image
chartist in reply to MBAnderson

FMT = Fecal Microbiome Transplant, what I have been talking about for the past 3 years.

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

FMT has pretty much worked out as we discussed 3 years ago and to me looks like the best viable option for PwP now that the FMT study has been released and the red light/PBM study has been released. The combination of PBM and FMT looks like the fastest way to significant improvement for PwP.

Art

If you change your name to Winnie the Poo there's going to be a copyright action Art

Oh POO! 😷😷😷

LindaP50 profile image
LindaP50 in reply to JAS9

Integrative medicine suggest eating fermented foods as well for leaky gut/gut bacteria.Homemade yogurt (easy to make and gave husband focus on his own health as he was the one to make the yogurt).

Kimchi, sauerkraut, pickles ...

What kind of skin problems did you have?

If it's seborheic dermatitis you could have had an anti fungal for Malessia, the later being neurotoxic and able to break the blood/brain barrier.

If not, this is the same as what happened to Pr Borody (Australia) whose patient was healed from PD after having a very strong antibiotic treatment for Clostridium difficile.

professor profile image
professor in reply to Xenos

THIS LOOKSAS THOUGH WE HAVE THHE ANSWER CLAITHROMYCYLIN.

All of these are intriguing ideas and would like to see more discussion about them.

rescuema profile image
rescuema in reply to MarionP

It may only apply to a subset of PWP, but fungal or bacterial could be the disease pathology for some. Watch the below

youtube.com/watch?v=ETKZS5e...

professor profile image
professor in reply to MarionP

marion read thetekspec in 30 years nothing has come closeCLARITHROMYCILIN

I tried the doxy for a while but no obvious improvement for me unfortunately. Might try it again.

What was the anti biotic

professor profile image
professor in reply to billPD

IT WASNT DOXYCILLINILL FIND OOUT

professor profile image
professor in reply to billPD

CLARITHROMOXOCYLIN i had to translatef rench in development

professor profile image
professor in reply to professor

claithromycylin

Some antibiotics are also anti-inflammatory

I’m also very curious about the antibiotic!! Want to know what it was; and what is the one that targets bad gut bacteria??

All of this talk about gut bacteria being linked to both the brain and the lungs make me wonder about these effects in Parkinson’s and COPD. My partner, the one who suffers from Parkinson’s disease, had his appendix taken out years ago. I’m wondering if there’s any link between the loss of an appendix and PD? Each time he’s been on antibiotics, sometimes for prostate or urinary infection, symptoms of COPD have cleared up. I’m not sure if it’s improved PD because we’re fairly new at treating it and there’s lots of flux ... Some days hardly any tremor (while on sinemet) and not so much freezing in legs; other days bad tremors and bad freezing. Lately lots of pain in legs and shoulders; and very bad cops cough. Wheezing. I really wanna try an antibiotic for bad gut. We Recently added miso soup daily, and are trying other foods with probiotics to increase healthy gut bacteria. But I think this in combination with antibiotics would be good!! Any thoughts?!

professor profile image
professor in reply to Scrudgie

listen this was a surprise to me i went from 15% mobility to98 this is a game changerCLARITHROMYCLIN .....pink champagne on ice we are all jus prisioners here of ourown device..................whats the song

Levod profile image
Levod in reply to professor

Hotel California

"...Last thing I remember, I was

Running for the door

I had to find the passage back

To the place I was before

"Relax, " said the night man,

"We are programmed to receive.

You can check-out any time you like,

But you can never leave! ..."

Is this song a metaphor for PD? Eery....

professor profile image
professor in reply to Levod

it wasa game changer for me head music instead of head bangin music ok lets make it a bit more difficlt GERRIMIA WAS A BULLFROG WAS A GOOD FRIEND OF MINE song artist year

Levod profile image
Levod in reply to professor

I don't know, but I remember some of the words... "Joy to the fishes in the deep blue sea; Joy to you and me..."

billPD profile image
billPD in reply to professor

Joy to the World; Three Dog Night

billPD profile image
billPD in reply to professor

Are you still taking it and how do you feel now?

We should all be careful not to reduce a very complex situation (gut biome health) to a single solution ("CLARITHROMYCIN"). This can be a big mistake and can cause other problems that you don't need. As an example, consider this case which is discussed by a nutrition and gut health expert. The 'patient' was an otherwise quite healthy individual who accidentally triggered some gut issues simply by fasting:

youtu.be/eaa3tNQ_XI8

clinicaltrials.gov/ct2/show...

so many negtuve waves we are all fucked unless yu rollthe dice i was willing to share my amaxing discovery with yu to give the parkys hope and not 1 of yu said thats good. shouldyu not be asking for how best we can move forward

alexask profile image
alexask in reply to professor

Killing multiple bacteria through continuous use of antibiotics is probably not a long term solution. However this does point to bacteria being an issue. This does suggest that using probiotics to seed good bacteria in your stomach may be an idea. Also mannitol may also be beneficial.

chartist profile image
chartist in reply to professor

professor,

Of course it is good to improve or eliminate PD symptoms as you described, but if it is not accessible or has long term health ramifications of its own, then is it really good as a treatment for PwP? if your doctor won't prescribe it how would anyone get it? The side effects from long term and even short term antibiotic use can be severe and Clarithromycin is "not compatible with many drugs" and has significant side effects, that with long term use, as would be required for PwP, are more likely to occur.

mayoclinic.org/drugs-supple...

Clarithromycin is also known to kill good gut bacteria which will in time create more health problems :

bmjopen.bmj.com/content/10/....

Lastly, Clarithromycin is linked with heart death :

medicalxpress.com/news/2014...

I understand your excitement about Clarithromycin because of the temporary effects that you experienced, but long term use of Clarithromycin does not seem like a viable solution for PwP because of not being available and health and safety concerns.

Art

LindaP50 profile image
LindaP50 in reply to chartist

When husband was being treated for Lyme Disease (which morphed into PD) and taking a few different types of antibiotics and supplements, he had to take blood tests every few weeks to make sure they weren't doing more harm then good. Had to stop all RX and supplements for a month as they were started to affect his kidneys. At that point he was working on the gut with probiotics and fermented foods.

I would like to visit the other point mentioned by professor which is that the dopamine-producing cells in the brain AREN'T causing symptoms by DYING. They stop making dopamine, but they're STILL ALIVE.

I remember an article or study about this startling and encouraging discovery not very long ago. Does anybody remember that piece, and/or have a link to it?

Realizing the cells are still alive calls for a whole new set of questions like... is the way the cell makes dopamine separate from the way it keeps itself alive? if so, what's happening to/inside the cell that stops it from making dopamine but doesn't kill it? how do things like B-1 and/or certain antibiotics turn dopamine production on again?

BTW, professor's experience with the antibiotic sounds a LOT like my own experience with my VERY FIRST dose of B-1 -- 12 HOURS after my FIRST dose of B-1, I regained 90+% of my functionality, and the effect lasted for hours. (I take my right dose of B-1 every day now and can't imagine doing without it.)

My point is that the corpses of dead brain cells don't hang around like tiny Frankenstein monsters waiting to be re-animated. Dead cells are DEAD, and as such are promptly destroyed and the bits cleared away.

Only LIVING cells remain in place. Only LIVING cells can have their dopamine-making process 're-activated' this way.

And this new info is indeed a game-changer; it means there are potentially WAY more cells available to make dopamine than anybody thought; and it looks to me like a big ole neon sign pointing in a promising direction for resarch. This could be the key that unlocks what's really going on with PD and how many ways there might be to change, interrupt, or reverse it.

Anybody up for finding and following any researchers focused on getting those non-producing brain cells back into production? Art, any interest there?

Thanks in advance.

chartist profile image
chartist in reply to T-Writer

T-Writer,

Based on the Fecal Microbiome Transplant (FMT) study results, it would appear that your idea of the neurons not being dead but rather in a senescent state may be worth further investigation. In the FMT study, improvement in UPDRS ll scoring was significant, suggesting that DA neurons production of dopamine may have increased or senescent neurons were reactivated . There is another consideration that the FMT study might suggest and that is that DA neuron activity is determined by the gut bacteria. If a late stage PwP could be brought back to an earlier stage, then either idea of senescence or gut bacteria control might be a possibility. That would require a significant amount of study and testing to attempt to answer those questions.

professor did not say what stage he was at when he achieved his extraordinary results, but more advanced stage would add more substance to these ideas.

My impression is that the earlier in the disease process a remedy is applied, the better the chances that it will work.

Although the idea of senescence or gut bacterial control of DA neurons sounds interesting and worth pursuing, the results obtained in the FMT study is almost available and LED/laser/near infrared red light therapy or Photobiomodulation (PBM) as it is called, is here and available now. All that is needed for the red light therapy is for the Australian PBM study results to be released and that is supposed to happen in September of this year. If those results look anything like the results from the FMT study, then PBM seems like it is the way forward and PBM is already available, so will funding be directed at the idea of senescence or gut bacterial control of DA neurons? If a viable treatment for PD, with the use of PBM is already available, I am doubtful such research into the possibility of senescence of DA neurons or gut bacterial control of DA neurons will move forward.

Even if the Australian PBM results are disappointing, which seems unlikely based on the results of the San Francisco PBM study as well as the buzz around the Australian study, FMT is just around the corner so to speak.

Art

professor profile image
professor in reply to chartist

chartist iv had parkinsons32 yers THE can yu imagine having full navigation full balance ffrom having virtuallly zero and can i just say i was surprised completely un preparedfor it said to consulmtant I THINK THISNEEDS MAJOR FLAG BUT i was poopooed

investigating why it worked the DRUGorigin FReNCH i was gobsmacked certain key abilities of it haave bEEN DROPPED

@ INUK DESCRIPTIONNO WHERE DOES IT SAT TREATS PD ALTHOUGH IT HAS THE TOOLS

CLEARLY THEY WERE HIDING THIS

I BELIEVECLAITHROMYCIN IS AVAILAABLE ON LINE

THE POWER OF THOSE WHO CONTROL

chartist profile image
chartist in reply to professor

professor,

I can't argue with your reasoning especially given your elapsed time since diagnosis. Yes, it deserves further investigation to get to the truth of the matter, to be sure. There is so much money at stake though and when it is that large of an amount of money, getting to the truth can often be more than difficult if not impossible.

Art

Art. Wake up and smell the roses. And look at the profs history. PD is attributable to eating pork, which is presumably why Jews and Muslims don't suffer from it.ALTHOUGH IT NEEDS CAPITALS TO MAKE THE POINT

IT'S ANOTHER CONSPIRACY THEORY. THE SOLUTION IS THAT SIMPLE. THE FUCKERS re hidden it from us

Well, when you put it that way, I'm off to get a dozen roses! 😦Thank you for the heads up Mr. Poo! I didn't think much of it because others have reported benefit from Doxy, but not as robust as what professor described. I should have checked the felonious facts!

Art

professor profile image
professor in reply to chartist

on this fforum i asked 7 years ago why muslims dont eat pork no one repliedART has ... IF THERE IS NO WITNESS OF PD IN JEWS OR MUSLIMS AHM GONNA SELL MA PIG FARM..L.O.L WATCH THE SHIT HIT THE FAN NOW................... WE HAVE SOLUTIONMAYBEWEHAVECOME SO FAR

Juliegrace profile image
Juliegrace in reply to professor

There is a higher incidence of PD amongst Ashkenazi Jews and some Arab Bedouins so this thing about no pork consumption is NONSENSE. Do the research.

professor profile image
professor in reply to Juliegrace

what is reason they must not eat pork(aprt from religous

I have done a little googling and you may be onto something.One study seems to show that this antibiotic can result in a higher availability of dopamine, as it suppresses something that reduces dopamine in the brain.

This is definitely worth following up, and I’ll test it myself when I can get my hands on some.

Thanks for sharing.

Oceanwind profile image
Oceanwind in reply to Astra7

I also found this to be true - I got relief from an antibiotic. It was about eight years ago. I felt incredibly changed and super happy that my symptoms had gone away and I felt like doing a happy dance and hugging strangers on the street! I told my doctor about it and begged her to give me more. It was initially prescribed for an ear infection. When she looked in my ear she told me It was still a little pink… So I was thrilled that I could have one more lot for another week but surprisingly, (to me at the time...)my Parkinson’s symptoms came back that second week.

Anyway I have wondered about that since that remarkable week.

Do you have any sources that you found that you could share with me regarding your discovery? I’m really curious!

professor profile image
professor in reply to Oceanwind

what was the antibiotic my antibiotic isnot doxy

Oceanwind profile image
Oceanwind in reply to professor

Can’t recall. I’ll ask my doctor next time I chat with her. Hopefully it’s in her notes.

Gut Health - Ben Warren's top 10 tips for a healthy gut.

youtube.com/watch?v=SRdEEC4...

youtube.com/watch?v=6IRWWhQ...

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