Pioneering neural recordings lay the groundwork for personalized Parkinson's treatments

[Farooqji]

In a study published May 3rd in Nature Biotechnology, UCSF Weill Institute for Neurosciences researchers implanted novel neurostimulation devices that monitor brain activity for many months, with and without deep brain stimulation (DBS) therapy. Pairing the brain recordings with wearable monitors of movement, they identified patterns of brain activity corresponding to specific movement abnormalities associated with Parkinson's. Their research provides the first evidence, during normal activities of daily living, for a long-held hypothesis that Parkinson's symptoms are related to erratic brain wave patterns, and demonstrate how DBS restores order to patient brain waves.

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[Mimer]

Very interesting. The study provides more evidence to back up the hypothesis that the symptoms are related to erratic brain wave patterns.

It also opens up for a new generation of DBS devices. Feedback on the result of the stimulation opens up for adaptive algorithms and AI to control the DBS signal. It will be a huge difference compared with today's technology. It minimizes the risk of an unsuccessful implementation and will most likely increase the efficiency of the treatment.

[Despe in reply to Mimer]

Still, a very invasive procedure. It might be worth evaluating PTT as an approach.