CBD is a substance with poor systemic blood exposure. One scientist explains the challenge and what it means

[Farooqji]

Based on the available commercial literature, CBD is being touted as a remedy for addiction, aging, anxiety, arthritis, concussion, depression, nausea, obesity, pain, Parkinson’s disease, post-traumatic stress disorder, and psychiatric disorders, among others. However, no evidence of double-blinded, placebo-controlled clinical trials that supported these claims could be located by the author, and anecdotal claims of CBD therapeutic utility often arise from what are actually inconclusive studies

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