Mucuna and blood thinners

[Laua]

Hello all

Anyone taking Mucuna together with blood thinners?

I would like to start taking Mucuna from Supersmart but since I am on blood thinners(Apixaban),I would like to know if there may be any interactions.

Can not get an answer from my neurologist as he doesn t believe in mucuna..

Your feedback would be much appreciated ,Thanks!

Laua

[WinnieThePoo]

Since the active substance in Mucuna is Levadopa , and Sinemet has no contraindications with blood thinners (my Stepfather was on warfarin and Sinemet, and my father was on Apixaban and Sinemet) then you should be fine

[Laua in reply to WinnieThePoo]

Hi Winnie,thank you so much for your feedback,I ve been looking for that answer for at least a year and was worried there could be a counter-indication,but you are right makes total sense that if no counter-indication with synthetic levodopa,should be the same with natural levodopa.Thanks again!

[kevowpd in reply to WinnieThePoo]

Actual mucuna is like 95% other-stuff. Seems like a big call to make that its gonna be fine based on the 5% thats ldopa?

[WinnieThePoo in reply to kevowpd]

Cabbage and Brussels sprouts are 95% other stuff and I don't check with my pharmacist for contraindications before eating vegetables

[kevowpd in reply to WinnieThePoo]

Is that a reasonable analogy? Any contraindiction with a common supermarket vegetable is likely to get mentioned by the prescribing doctor. An obscure plant that isnt even that well understood by those that research it? Probably not.

[Spencer53]

Hwp is on Mucuna and Baby Asprin and we have not seen any problems.

[Laua]

Thanks all for your feedback,really helps.

[Hikoi in reply to Laua]

Laua I think you will have to decide. It is always a dilemma as many drugs we take together for PD are contra indicated. I agree with kevo — we dont know all the ingredients in mucuna. The article below specifically mentions and warns against blood thinners with mucuna.

From intechopen.com/books/parkin...

Specific warning about Mucuna

We assume that all contraindications, interactions, precautions, and side effects that we know about synthetic levodopa should be considered when taking levodopa from Mucuna.

Specific contraindications include thinning of the blood (anticoagulants), and care should be taken with antiplatelet and anti-inflammatory drugs because Mucuna increases clotting time. Mucuna should not merge with anticoagulants (Sintrom, Dabigatran, heparin, warfarin) or with antiplatelet drugs such as clopidogrel. Caution should be exercised, and the additive effect should be taken into account if it is associated with acetylsalicylic acid and nonsteroidal anti-inflammatory drugs (NSAIDs).

We should also be careful with antidiabetic medicines: Mucuna lowers glycemic index, and thus is to be considered a potential additive effect. Other interactions are possible, so always consult your regular doctor. On the one hand, it can be argued that Mucuna has been used for many centuries in India and has been available for several years online without a prescription, and yet serious problems have not been revealed. But that is just an observation.

Regarding Sinemet and Madopar, we have thousands of controlled studies, while publications on Mucuna are still scarce. One must therefore use greater caution when choosing Mucuna. While the future appears to be positive, we need the confirmation of more scientific studies.

[Laua]

Hi Hikoi,thanks so much for your post,I have seen Pr Maldonado article on the interactions and that is actually the reason why I m hesistant,however it seems some neurologists don t seem to be worried about these interactions,in fact I had a teleconsultaion with a neurologist in the US(not my own neurologist) to have his view and he said I could try Mucuna and see if works..which is why I am a little lost