Symptoms of PD differ between the genders with women suffering more from anxiety, depression and dyskinesia to mention a few. Women also suffer symptom fluctuations for many reasons such as hormonal fluctuations and body weight. However, treatment of women with PD remains the same regardless of these differences. This PD Avengers webinar hosted by Cure Parkinson's discusses the difference of living with Parkinson's as a woman and whether solving some of the specific symptoms may actually open up the possibility of new and better treatments for all suffering from PD.
Hi - the webinar was yesterday - I'm sorry that you missed it. We will be presenting the recording on our website within the next few days if this helps. Thank you for your interest.
Thanks for posting the link to the recorded video. I am intrigued by this topic "whether solving some of the specific symptoms may actually open up the
possibility of new and better treatments for all suffering from PD."
We don't need more treatments we need a cure! We already have ways to reverse many of the movement symptoms, so why don't we encourage patients to take advantage of them and get on with their lives as I have. I am 86 years old and have had Pd symptoms for 58 years, but was only diagnosed with Pd 39 years ago, I have lived, Pd medication-free for the past 19 years
Hi John - My wife Paulette has had Parkinson's (slow onset) for the past 25-30 years. Unfortunately she has succumbed to the lethargy and apathy that seems to be an unavoidable symptom of either the disease or the (various) medications (including Levo/Carb/Sinemet) she's been taking as suggested by her PD specialists here in Richmond/Vancouver BC (out of UBC).
I've been wondering if you have had a similar set of symptoms to over come or if your active walking (and other supplements/vitamins/drugs?) have helped you avoid the 'giving up hope' problem?
Please note that this is after we, a few years ago, attended a PD active movement clinic in Scottsdale for a week of PD specific exercises, poll walking and, and noticed a SIGNIFICANT physical improvement...that faded almost as fast as we got back home and the lethargy took over. Lately even getting out of the house is unusual for her.
Hi KenS, Pd medication does nothing to reverse the symptoms of Pd, we just have to take more and more until they cease to work anymore and the patient is left in a no-win situation.
Whether she can start doing exercise at this late stage is not guaranteed. But the result of the exercise session you went to, tells me that done properly could very definitely bring the results needed, but it takes a long time, slowly getting better, not worse!
May I suggest you buy my book, "Reverse Parkinson's Disease", from Amazon , gives you my whole story and all the symptoms and what I did about them. I will help you in any way I can. If you give me your email address I will send my videos and some important information, in a separate email.
I would also like to see your videos. I don't want to start medication. A hip/groin injury has limited my ability to exercise. Any help would be appreciated. Planning on purchasing your book. Thanks for the hope
"Symptoms of PD differ between the genders with women suffering more from anxiety, depression and dyskinesia to mention a few."
I think you are confusing the word "symptoms" with "incidence", "prevalence", "onset", "progression" and perhaps "mortality".
Haaxma and colleagues (2007) "found specific male-female differences in the presentation of PD (4). The women were on average 2.1 years older than the men at time of diagnosis (53.4 vs 51.3 years) and were more likely to present with tremor as their initial symptom than with bradykinesia or rigidity. "
From Miller (2010): "Once the disease reached its clinical stage (i.e. formal diagnosis by a qualified physician), no male-female differences were seen, meaning that estrogen was important in neuroprotection but offered no benefit once the disease had manifested itself clinically.
From Cerri (2019): "women have a higher mortality rate and faster progression of the disease." (debatable according to Tanner, 1996)
For those interested in sex differences in biology and medicine, I highly recommend the NUS Medicine's webinar series, 'Making Reproductive Longevity a Reality',
I have learned quite a few interesting little things from this series, for example - the most sexually dimorphic organ apart from the sex organs themselves is the liver.
I think there is more to the story than estrogen and a lot more to learn from studying sex differences in the PD disease process. I'm interested in sex differences in the immune system, especially mast cell function, and how that impacts neurodegenerative diseases.
The enthusiasm by some of the participants for biometric monitoring is encouraging .
One topic of research that could benefit women's health generally is how to delay onset of menopause.
Epidemiological studies have found associations with later onset of menopause with consumption of fresh legumes (e.g., English peas, green favas, green beans, edamame)*, oily fish and beta cryptoxanthin (found in mandarin oranges, papaya, etc.).
In vitro and mouse studies have found oocyte quality improved with increased CoQ10 and NAD+ levels. Oocyte quality governs the timing of menopause onset.
* aside from phytoestrogens, fresh legumes also contain biogenic amines such as spermidine
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