Compounds in Chinese Herbal Medicine May ... - Cure Parkinson's

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Compounds in Chinese Herbal Medicine May Treat Parkinson’s, Study Suggests

Farooqji profile image

Zhichan powder, a traditional Chinese medicine, contains several active compounds that may be of therapeutic value in Parkinson’s disease, researchers suggest.

parkinsonsnewstoday.com/202...

17 Replies

is this the same stuff (repackaged for a new article?)

healthunlocked.com/parkinso...

I assume it's another translation for zishenpingchan, or a slightly to moderately different formulation.

Gosh. How many supplements can we really take? Also, it’s a pain to add each of them to our medical records/ charts.

Not sure I’d be taking anything from China right now.

pdpatient profile image
pdpatient in reply to Astra7

Do you think you have a choice? Unless everything moves to India. Oh wait. Didn’t Trump just force India to send over a ton of that Malaria drug?

Erniediaz1018 profile image
Erniediaz1018 in reply to Astra7

Many of these herbs are grown and sold in Canada 🇨🇦 and the USA 🇺🇸

Most of the Mucuna comes from India.

This is only computational research rather than a clinical trial.

Where can I find it? Any idea?

Any idea where this powder can be bought?

Cant find this product

Yes where can we get it? I used to take some medicine for Asthma from a chinese shop it was fabulous. Then the shop closed.

Have you tried it iqbaliqbal? Or anyone since that post was made some time ago (mandersons link)?

You can get by prescription from an acupuncturist

Neural Regen Res. 2012 Sep 25; 7(27): 2107–2114.

doi: 10.3969/j.issn.1673-5374.2012.27.004

PMCID: PMC4281411

PMID: 25558223

Zhichan powder regulates nigrostriatal dopamine synthesis and metabolism in Parkinson's disease rats☆

Qingwei Zhou,1 Jiajun Chen, Ph.D.,2 Shihong Yi,3 Yongwei Lou,4 Weimin Tang,3 Yongmao Liu,3 and Pengguo Zhang5

ncbi.nlm.nih.gov/pmc/articl...

mybiohack.com/blog/zhichan-...

Zhichan regulates the expression of monoamine oxidase B and tyrosine hydroxylase in the substantia nigra of Parkinson’s disease rats, and facilitate the secretion of striatal dopamine and its metabolite homovanillic acid, resulting in a neuroprotective effect on substantia nigra neurons in Parkinson’s disease rats. R

Zhichan capsules have a down-regulation on the expression IL-1 β and TNF-α mRNA and an up-regulation on IL-6 and the T, B lymphocytes in PD mouse. R

2020;23(1):28-40.

doi: 10.2174/1386207323666200102124302.

Network Pharmacology Analysis on Zhichan Powder in the Treatment of Parkinson's Disease

Jia Li 1 , Xinchang Qi 2 , Yajuan Sun 1 , Yingyu Zhang 1 , Jiajun Chen 1

Aims and objective: Effective components and the mechanism of action of Zhichan powder for the treatment of Parkinson's disease were researched at a systematic level.

Materials and methods: Screening of active components in Zhichan powder for the treatment of Parkinson's disease was conducted using the Traditional Chinese Medicine Systems Pharmacology database, and a medicine-target-disease network was established with computational network pharmacology.

Results: By using network pharmacology methods, we identified 18 major active components in Zhichan powder through screening, indicating a connection between chemical components of this Traditional Chinese Medicine and Parkinson's disease-related targets.

Conclusion: The medicine-target-disease system of Zhichan powder established by network pharmacology permitted visualization of clustering and differences among chemical components in this prescription, as well as the complex mechanism of molecular activities among those effective components, relevant targets, pathways, and the disease. Thus, our results provide a new perspective and method for revealing the mechanism of action of Traditional Chinese Medicine prescriptions.

pubmed.ncbi.nlm.nih.gov/318...

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