New Canadian Poop...not Winnie the Pooh...but ... - CLL Support

CLL Support

22,509 members38,657 posts

New Canadian Poop...not Winnie the Pooh...but he was Canadian too!

Cllcanada profile image
CllcanadaTop Poster CURE Hero
1 Reply

Clostridium difficile kills CLL Patients...now Canadian discovery may help save lives...

From Scientifc American...

scientificamerican.com/podc...

'Stool substitute transplant therapy for the eradication of Clostridium difficile infection: ‘RePOOPulating’ the gut

When normal populations of healthy bacteria in the gut get out of whack, the result can be the stubborn and recurrent bacterial infection known as Clostridium difficile – C-dif. The main symptom is nearly constant and debilitating diarrhea.

One of the most successful therapies for C-dif is to repopulate the intestines with healthy bacteria that keep that nasty C-dif in check. There’s been only one way to do this: import a small sample of a healthy person’s feces. That’s right. A poop-transplant.

But the “ick” factor of fecal transplants is a hurdle for some, as well as a regulatory conundrum for the FDA. Which is why researchers at the University of Guelph in Canada came up with a synthetic alternative: a laboratory-made slurry of healthy bacteria they’re calling “rePOOPulate.” The research is published in the journal Microbiome. [Elaine O. Petrof et al., Stool substitute transplant therapy for the eradication of Clostridium difficile infection: "RePOOPulating" the gut]

It’s intended to replace human fecal matter in stool transplants, and researchers say it has several advantages. The bacteria are carefully controlled and can be tailored to the patient. It reduces the risk of transmitting disease. And, well, it’s just less gross.'

microbiomejournal.com/conte...

Pooh Bear

en.wikipedia.org/wiki/Winni...

Thanks Neil for your link!

Written by
Cllcanada profile image
Cllcanada
Top Poster CURE Hero
To view profiles and participate in discussions please or .
Read more about...
1 Reply
HAIRBEAR_UK profile image
HAIRBEAR_UKFounder Admin

Interesting scoop Chris!

Have posted another Pooh Bear favourite. (- : In the fight against Clostridium difficile

You may also like...

Curbing Fluoroquinolone Antibiotics Tied to Britain's Drop in C.Diff

about how difficult it is to eradicate a Clostridium difficile infection. So I was interested to...

Weekly Dose: penicillin, the mould that saves millions of lives

antibiotics, penicillins can lead to infection with Clostridium difficile, an organism that causes...

Revealed: the gut microbiome varies through the day and through the seasons

reported research...

Good news on vaccine efficacy for the 80%

\\" https://www.cell.com/cancer-cell/pdf/S1535-6108(22)00212-4.pdf Extracts: Spike-specific...

Lymphangitis - red streaks under your skin require urgent attention!

intended for secondary respiratory infections not skin infections), so I decided to check again...